Lessons learned to date on COVID-19 hyperinflammatory syndrome: considerations for interventions to mitigate SARS-CoV-2 viral infection and detrimental …

M Cardone, M Yano, AS Rosenberg… - Frontiers in …, 2020 - frontiersin.org
The first case of human transmission of SARS-CoV-2 was reported in China in December
2019. A few months later, this viral infection had spread worldwide and became a pandemic …

Mechanism of cytokine storm syndrome in COVID-19

R Harfouch - Authorea Preprints, 2022 - advance.sagepub.com
Mechanism of cytokine storm syndrome in COVID-19 Page 1 P osted on Authorea 23 F eb
2022 — The cop yrigh t holder is the author/funder. All righ ts reserv ed. No reuse without p …

Targeting Specific Checkpoints in the Management of SARS-CoV-2 Induced Cytokine Storm

A Rabiu Abubakar, R Ahmad, AB Rowaiye, S Rahman… - Life, 2022 - mdpi.com
COVID-19-infected patients require an intact immune system to suppress viral replication
and prevent complications. However, the complications of SARS-CoV-2 infection that led to …

[HTML][HTML] Cytokine storm and immunomodulation in COVID-19

P Rangappa - Indian Journal of Critical Care Medicine: Peer …, 2021 - ncbi.nlm.nih.gov
ABSTRACT COVID-19 has become a major pandemic in recent times. The exact
pathophysiology and understanding of cytokine storm and immunomodulation are evolving …

Macrophage activation syndrome and COVID-19

R Otsuka, K Seino - Inflammation and regeneration, 2020 - Springer
An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating
pandemic. As we have not developed curative medicine and effective vaccine, the end of …

Attenuating the effects of novel COVID-19 (SARS-CoV-2) infection-induced cytokine storm and the implications

AB Rowaiye, OA Okpalefe… - Journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic constitutes an arduous global health challenge, and the
increasing number of fatalities calls for the speedy pursuit of a remedy. This review …

Molecular modeling of C1‐inhibitor as SARS‐CoV‐2 target identified from the immune signatures of multiple tissues: An integrated bioinformatics study

K Sekaran, R Polachirakkal Varghese… - Cell Biochemistry …, 2023 - Wiley Online Library
The expeditious transmission of the severe acute respiratory coronavirus 2 (SARS‐CoV‐2),
a strain of COVID‐19, crumbled the global economic strength and caused a veritable …

Molecular and clinical prognostic biomarkers of COVID-19 severity and persistence

G Papadopoulou, E Manoloudi, N Repousi, L Skoura… - Pathogens, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), poses several challenges to clinicians, due to its …

SARS-CoV-2 induces “cytokine storm” hyperinflammatory responses in RA patients through pyroptosis

Q Zheng, R Lin, Y Chen, Q Lv, J Zhang, J Zhai… - Frontiers in …, 2022 - frontiersin.org
Background The coronavirus disease (COVID-19) is a pandemic disease that threatens
worldwide public health, and rheumatoid arthritis (RA) is the most common autoimmune …

[HTML][HTML] COVID-19: Targeting the cytokine storm via cholinergic anti-inflammatory (Pyridostigmine)

AH Osman - International Journal of Clinical Virology, 2020 - clinvirologyjournal.com
Background: The development of COVID-19 having been set apart as the third presentation
of an exceptionally pathogenic coronavirus into the human populace after the extreme …