Intravital microscopy has been recognized for its ability to make physiological
measurements at cellular and subcellular levels while maintaining the complex natural …

Since its invention 29 years ago, two‐photon laser‐scanning microscopy has evolved from a
promising imaging technique, to an established widely available imaging modality used …

Intravital multiphoton microscopy is widely used to assess the structure and function of
organs in live animals. Although different tissues vary in their accessibility for intravital …

Metastasis to secondary sites such as the lung, liver and bone is a traumatic event with a
mortality rate of approximately 90% 1. Of these sites, the lung is the most difficult to assess …

In vivo microscopy has recently become a gold standard in lung immunology studies
involving small animals, largely benefiting from the democratization of multiphoton …

Two‐photon excitation fluorescence microscopy and backscattered‐second harmonic
generation microscopy permit the investigation of the subcellular events within living …

Tissues are heterogeneous with respect to cellular and non-cellular components and in the
dynamic interactions between these elements. To study the behaviour and fate of individual …

Serial intravital 2-photon microscopy of the kidney and other abdominal organs is a powerful
technique to assess tissue function and structure simultaneously and over time. Thus, serial …

In vivo microscopy is a powerful method for studying fundamental issues of physiology and
pathophysiology. The recent development of multiphoton fluorescence microscopy has …

Recent advances in intravital microscopy have provided insight into dynamic biological
events at the cellular level in both healthy and pathological tissue. However, real-time in vivo …