COVID-19 and the nicotinic cholinergic system

K Farsalinos, A Angelopoulou… - European …, 2020 - Eur Respiratory Soc
We have read with great interest the paper by Leung et al.[1] published in the European
Respiratory Journal, the correspondence by Russo et al.[2], and also the subsequent …

COVID-19 and nicotine as a mediator of ACE-2

JM Leung, CX Yang, DD Sin - European Respiratory Journal, 2020 - Eur Respiratory Soc
We recently reported that current smokers and those with COPD had higher airway epithelial
cell expression of the angiotensin-converting enzyme II (ACE-2) viral entry receptor [1]. We …

COVID-19 and smoking: is nicotine the hidden link?

P Russo, S Bonassi, R Giacconi… - European …, 2020 - Eur Respiratory Soc
Leung et al.[1] have recently published, in the European Respiratory Journal, a paper on the
expression of angiotensin-converting enzyme II (ACE-2) in the small airway epithelia of …

Current smoking is not associated with COVID-19

M Rossato, L Russo, S Mazzocut… - European …, 2020 - Eur Respiratory Soc
We have read with interest the paper by Leung et al.[1] recently published in the European
Respiratory Journal, reporting a higher expression of the protein angiotensin-converting …

Nicotine and the nicotinic cholinergic system in COVID‐19

Y Tizabi, B Getachew, RL Copeland… - The FEBS …, 2020 - Wiley Online Library
There is an urgent need to address the devastating pandemic, COVID‐19, caused by SARS‐
CoV‐2. The efforts to understand the details of this disease in hope of providing effective …

[HTML][HTML] A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications

JP Changeux, Z Amoura… - Comptes …, 2020 - comptes-rendus.academie-sciences …
SARS-CoV-2 epidemics raises a considerable issue of public health at the planetary scale.
There is a pressing urgency to find treatments based upon currently available scientific …

Potential role of memantine in the prevention and treatment of COVID-19: its antagonism of nicotinic acetylcholine receptors and beyond

S Hasanagic, F Serdarevic - European Respiratory Journal, 2020 - Eur Respiratory Soc
Recently, Leung et al.[1] proposed that α7-subtype nicotinic acetylcholine receptor (α7-
nAChR) antagonists might decrease angiotensin-converting enzyme (ACE) 2 receptor …

[HTML][HTML] Nicotine and SARS-CoV-2: COVID-19 may be a disease of the nicotinic cholinergic system

K Farsalinos, R Niaura, J Le Houezec… - Toxicology …, 2020 - ncbi.nlm.nih.gov
As of 20 April, almost 1.7 million people globally have been diagnosed with Corona Virus
Disease 2019 (COVID-19), a pandemic that has evolved from the emergence of a new …

Beyond smoking cessation: investigating medicinal nicotine to prevent and treat COVID-19

HA Tindle, PA Newhouse… - Nicotine and Tobacco …, 2020 - academic.oup.com
In the absence of treatment or a vaccine, the SARS-CoV-2 pandemic challenges the medical
community to identify novel containment strategies. Changeux et al. 1 have proposed the …

Reply to:“Current smoking is not associated with COVID-19”

JM Leung, CX Yang, DD Sin - European Respiratory Journal, 2020 - Eur Respiratory Soc
Like M. Rossato and co-workers, we too have been struck by the relative
underrepresentation of current smokers in cohorts of coronavirus disease 2019 (COVID-19) …