Purpose: NOV03 has a unique dual mode of action to address dry eye disease (DED)
associated with meibomian gland dysfunction. SEECASE evaluated the efficacy, safety, and …

Objective To evaluate the efficacy and safety of NOV03 (perfluorohexyloctane) ophthalmic
drop in patients with dry eye disease (DED) associated with meibomian gland dysfunction …

Purpose To evaluate the efficacy and safety of NOV03 (perfluorohexyloctane) ophthalmic
drop for the treatment of signs and symptoms of dry eye disease (DED) associated with …

Purpose To evaluate the safety and efficacy of OTX-101, a novel aqueous nanomicellar
formulation of cyclosporine (0.09%), in the treatment of patients with dry eye disease (DED) …

Purpose The aim of this study was to evaluate the safety and efficacy of OTX-101, a clear
nanomicellar aqueous solution of cyclosporine, in the treatment of dry eye disease (DED) …

Purpose To evaluate the efficacy and safety of OC-01 (varenicline solution) nasal spray for
treatment of patients with dry eye disease. Design Randomized, multicenter, double …

Keratoconjunctivitis sicca, also known as dry eye disease (DED), is a prevalent,
multifactorial disease associated with compromised ocular lubrication, ocular surface …

OBJECTIVE: To explore the safety and efficacy of CF101, an A3 adenosine receptor agonist,
in patients with moderate to severe dry eye syndrome. DESIGN: Phase 2, multicenter …

Dry eye disease (DED) is a multifactorial and complex disease of the ocular surface, with a
high prevalence in adults. We systematically reviewed efficacy and safety data from …

Abstract Introduction This Phase 2 clinical trial assessed the efficacy and safety of the novel
antioxidative, renewable compound SkQ1 for topical treatment of dry eye signs and …