Alzheimer's disease (AD) is the most common form of dementia and it is characterized by the
deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain. However, the …

Alzheimer's disease (AD), the most common cause of dementia, is a complex and
multifactorial disease involving genetic and environmental factors, with …

Alzheimer's disease (AD) is a gradually debilitating disease that leads to dementia. The
molecular mechanisms underlying AD are still not clear, and at present no reliable …

In recent decades, the impairment of cholesterol metabolism in the pathogenesis of
Alzheimer's disease (AD) has been intensively investigated, and it has been recognized to …

The development of Alzheimer's disease (AD) is influenced by several events, among which
the dysregulation of cholesterol metabolism in the brain plays a major role. Maintenance of …

Since the discovery of the significance of the cholesterol-carrying apolipoprotein E and
cholesterolaemia as major risk factors for Alzheimer's Disease (AD) there has been a …

Alzheimer's disease (AD), the most common form of dementia, is characterized by the
progressive loss of neurons and synapses, and by extracellular deposits of amyloid‐β (Aβ) …

Mechanisms for the regulation of intracellular cholesterol levels in various types of brain and
vascular cells are of considerable importance in our understanding of the pathogenesis of a …

The implication that cholesterol plays an essential role in the pathogenesis of Alzheimer's
disease (AD) is based on the 1993 finding that the presence of apolipoprotein E (apoE) …

A link between alterations in cholesterol homeostasis and Alzheimer's disease (AD) is
nowadays widely accepted. However, the molecular mechanism/s underlying such link …