Biomarkers in relation to cognitive reserve in patients with mild cognitive impairment–proof of concept

S Rolstad, A Nordlund, C Eckerström… - Dementia and geriatric …, 2009 - karger.com
Background: The concept of the cognitive reserve (CR) posits that factors such as education
enable compensation for the effect of brain pathology. Consequently, pathology should be …

Cognitive reserve in relation to abeta42 in patients converting from MCI to dementia–a follow-up report

S Rolstad, A Nordlund, C Eckerström… - Dementia and geriatric …, 2009 - karger.com
The concept of the cognitive reserve (CR) hypothesizes that premorbid factors such as
education enable compensation for the manifestation of brain pathology. Accordingly …

Neurocognitive deficits and effects of cognitive reserve in mild cognitive impairment

N Andrejeva, M Knebel, V Dos Santos… - Dementia and geriatric …, 2016 - karger.com
Background/Aims: Mild cognitive impairment (MCI) is a frequent syndrome in the older
population, which involves an increased risk to develop Alzheimer's disease (AD). The latter …

The dual role of cognitive reserve in subjective cognitive decline and mild cognitive impairment: a 7-year follow-up study

S Mazzeo, S Padiglioni, S Bagnoli, L Bracco… - Journal of …, 2019 - Springer
The aim of this study was to evaluate the effect of cognitive reserve (CR), in progression from
subjective cognitive decline (SCD) to mild cognitive impairment (MCI) and Alzheimer's …

High education may offer protection against tauopathy in patients with mild cognitive impairment

S Rolstad, A Nordlund, C Eckerström… - Journal of …, 2010 - content.iospress.com
The concepts of brain and cognitive reserve stem from the observation that premorbid
factors (eg, education) result in variation in the response to brain pathology. Potential early …

Role of cognitive reserve in progression from mild cognitive impairment to dementia

RF Allegri, FE Taragano, H Krupitzki… - Dementia & …, 2010 - SciELO Brasil
Cognitive reserve is the ability to optimize performance through differential recruitment of
brain networks, which may reflect the use of alternative cognitive strategies. Objectives: To …

Life-course determinants of cognitive reserve (CR) in cognitive aging and dementia–a systematic literature review

D Chapko, R McCormack, C Black, R Staff… - Aging & mental …, 2018 - Taylor & Francis
Objectives: The concept of cognitive reserve (CR) is defined as a moderator, which allows
an individual to preserve cognition despite underlying brain pathology. There is no …

Cognitive reserve and the risk for Alzheimer's disease: a longitudinal study

L Serra, M Musicco, M Cercignani, M Torso… - Neurobiology of …, 2015 - Elsevier
This study investigates how cognitive reserve (CR) interacts with neurodegeneration
(quantified by medial temporal atrophy, MTA) and macroscopic white matter lesions (WMLs) …

[HTML][HTML] Neuronal injury biomarkers for assessment of the individual cognitive reserve in clinically suspected Alzheimer's disease

L Beyer, J Schnabel, P Kazmierczak, M Ewers… - NeuroImage: Clinical, 2019 - Elsevier
Objectives Many predictive or influencing factors have emerged in investigations of the
cognitive reserve model of patients with Alzheimer's disease (AD). For example, neuronal …

Cognitive and brain reserve in conversion and reversion in patients with mild cognitive impairment over 12 months of follow-up

A Osone, R Arai, R Hakamada… - Journal of clinical and …, 2016 - Taylor & Francis
Introduction: Two reserve hypotheses have been proposed to account for the observed
disjunction between the degree of brain pathology and its clinical manifestations. This study …