Ribonuclease Dicer belongs to the family of RNase III endoribonucleases, the enzymes that
specifically hydrolyze phosphodiester bonds found in double-stranded regions of RNAs …

Dicers are multidomain proteins, usually comprising an amino-terminal putative helicase
domain, a DUF283 domain (domain of unknown function), a PAZ domain, two RNase III …

The Dicer ribonuclease plays a crucial role in the biogenesis of small regulatory RNAs
(srRNAs) by processing long double-stranded RNAs and single-stranded hairpin RNA …

Abstract Background Vertebrates have one Dicer ortholog that generates both microRNAs
(miRNAs) and small interfering RNAs (siRNAs), in contrast to the multiple Dicer-like proteins …

The RNase III endoribonuclease Dicer was discovered to be associated with cleavage of
double-stranded RNA in 2001. Since then, many advances in our understanding of Dicer …

The Dicer family of ribonucleases plays a key role in small RNA-based regulatory pathways
by generating short dsRNA fragments that modulate expression of endogenous genes, or …

RNase III Dicer produces small RNAs guiding sequence‐specific regulations, with important
biological roles in eukaryotes. Major Dicer‐dependent mechanisms are RNA interference …

Endoribonuclease III Dicer plays a crucial role in the biogenesis of small regulatory RNAs,
such as microRNAs (miRNAs) and small interfering RNAs (siRNAs). However, this is not the …

Dicer is a multidomain enzyme that generates small RNAs for gene silencing in eukaryotes.
Current understanding of Dicer structure is restricted to simple forms of the enzyme, whereas …

The RNA interference pathway (RNAi) is executed by two core enzymes, Dicer and
Argonaute, for accomplishing a tailored transcriptional and post-transcriptional gene …