Remdesivir was the first antiviral drug that received emergency use authorization from the
United States Food and Drug Administration and is now formally approved to treat COVID …

We combine sequence analysis, molecular dynamics and hybrid quantum
mechanics/molecular mechanics simulations to obtain the first description of the mechanism …

Antiviral drug therapy against SARS-CoV-2 is not yet established and posing a serious
global health issue. Remdesivir is the first antiviral compound approved by the US FDA for …

The efforts towards developing a potential drug against the current global pandemic, COVID-
19, have increased in the past few months. Drug development strategies to target the RNA …

The mechanism of remdesivir incorporation into the RNA primer by the RNA-dependent
RNA polymerase (RdRp) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV …

Recent efforts to repurpose drugs to combat COVID-19 have identified Remdesivir as a
candidate. It acts on the RNA-dependent, RNA polymerase (RdRp) of the SARS-CoV-2 …

RNA-dependent RNA polymerase (RdRp), also called nsp12, is considered a promising but
challenging drug target for inhibiting replication and hence, the growth of various RNA …

The binding of the active form of Remdesivir (RTP) to RNA-dependent RNA Polymerase
(RdRp) of SARS-CoV-2 was studied using molecular dynamics simulation. The RTP …

The RNA-dependent RNA polymerase (RdRp) is a key enzyme which regulates the viral
replication of SARS-CoV-2. Remdesivir (RDV) is clinically used drug which targets RdRp …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) relies on the central
molecular machine RNA-dependent RNA polymerase (RdRp) for the viral replication and …