Single-cell transcriptomic analysis reveals a systemic immune dysregulation in COVID-19-associated pediatric encephalopathy

Y Wang, LDW Luu, S Liu, X Zhu, S Huang… - … and Targeted Therapy, 2023 - nature.com
Unraveling the molecular mechanisms for COVID-19-associated encephalopathy and its
immunopathology is crucial for developing effective treatments. Here, we utilized single-cell …

Case report: Distinct neurologic manifestation and cytokine profile of a child with COVID-19-associated acute fulminant encephalitis

YM Chang, CH Chen, JN Wang, CM Cheng… - Frontiers in …, 2023 - frontiersin.org
The neurologic manifestations of coronavirus disease 2019 (COVID-19) may range from
mild symptoms such as headache or confusion to profound encephalopathy with variable …

Pathogenesis and preventive tactics of immune-mediated non-pulmonary COVID-19 in children and beyond

H Chi, L Chang, YC Chao, DS Lin, HW Yang… - International Journal of …, 2022 - mdpi.com
The COVID-19 pandemic has evolved to immune escape and threatened small children and
the elderly with a higher severity and fatality of non-pulmonary diseases. These life …

COVID-19-associated monocytic encephalitis (CAME): histological and proteomic evidence from autopsy

PP Zhang, ZC He, XH Yao, R Tang, J Ma… - … and Targeted Therapy, 2023 - nature.com
Severe neurological symptoms are associated with Coronavirus disease 2019 (COVID-19).
However, the morphologic features, pathological nature and their potential mechanisms in …

Acute necrotizing encephalopathy in children with COVID-19: a retrospective study of 12 cases

X Lin, Y Wang, X Li, M Abdalla, F Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Acute necrotizing encephalopathy (ANE) is a devastating neurologic condition
that can arise following a variety of systemic infections, including influenza and SARS-Cov …

[PDF][PDF] Reply to the letter “COVID-19-associated encephalopathy and cytokine-mediated neuroinflammation”

A Pilotto, A Padovani, N ENCOVID-BIO - Ann Neurol, 2020 - researchgate.net
Muccioli et al proposed an interesting comparison between the case of encephalitis related
to severe acute respiratory syndromecoronavirus 2 (SARS-CoV-2) infection we described …

Immune mediating molecules and pathogenesis of COVID-19-associated neurological disease

HO Singh, A Singh, AA Khan, V Gupta - Microbial Pathogenesis, 2021 - Elsevier
Background Long period of SARS-CoV-2 infection has been associated with psychiatric and
cognitive disorders in adolescents and children. SARS-CoV-2 remains dormant in the CNS …

[PDF][PDF] Acute encephalopathy in a child with coronavirus disease-2019 infection

A Kinikar, R Kulkarni, U Rajput, R Karyakarte - Pediatr Infect Dis, 2020 - pidjournal.com
ABSTRACT Coronavirus disease-2019 (COVID-19) is a global health crisis. Children
account for 1–5% of diagnosed COVID-19 cases with relatively mild presentation and less …

Central neuroinflammation in Covid-19: a systematic review of 182 cases with encephalitis, acute disseminated encephalomyelitis, and necrotizing encephalopathies

R Zamani, R Pouremamali, N Rezaei - Reviews in the Neurosciences, 2022 - degruyter.com
Growing evidence demonstrates the association of encephalitis, meningoencephalitis or
encephalomyelitis, with SARS-CoV-2 infection. This study aims to determine the profile and …

Neurologic manifestations of COVID-19 in children: emerging pathophysiologic insights

ME Schober, AT Pavia… - Pediatric Critical Care …, 2021 - journals.lww.com
In adults with COVID-19 (the disease caused by infection with severe acute respiratory
syndrome coronavirus, SARS-CoV-2), the prevalence of acute neurologic symptoms (eg …