Exosomes are a subtype of membrane vesicle released from the endocytic compartment of
live cells. They play an important role in endogenous cell-to-cell communication. Previously …

In the last few decades, RNA-based drugs have emerged as a promising candidate to
specifically target and modulate disease-relevant genes to cure genetic defects. The key to …

Gene vectors are nucleic acids that carry genetic materials or gene editing devices into cells
to exert the sustained production of therapeutic proteins or to correct erroneous genes of the …

Clinical treatments have stalled in certain diseases due to a lack of proper therapeutic
delivery systems. Recent studies have identified exosomes for their potential use as cell-free …

Exosomes are biological membrane vesicles measuring 30 to 100nm. They contain an
abundance of small molecules like tetraspanins, receptors for targeting and adhesion, lipids …

Exosomes are naturally occurring extracellular vesicles released by most mammalian cells
in all body fluids. Exosomes are known as key mediators in cell‐cell communication and …

A major goal in biomedical research is to clinically reverse the cause of disease rather than
treating the symptoms. Gene therapy has the potential to meet this goal and the discovery of …

The science of gene therapy has experienced a controversial history. At first, the initial
concept that various disorders become curable by gene transferring was very exciting and …

Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …

Nanocarriers as drug/biomolecule delivery systems have been significantly developed
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …