Lassa fever—the road ahead

RF Garry - Nature Reviews Microbiology, 2023 - nature.com
Lassa virus (LASV) is endemic in the rodent populations of Sierra Leone, Nigeria and other
countries in West Africa. Spillover to humans occurs frequently and results in Lassa fever, a …

Current research for a vaccine against Lassa hemorrhagic fever virus

BM Warner, D Safronetz, DR Stein - Drug design, development and …, 2018 - Taylor & Francis
Lassa virus (LASV) is a rodent-borne arenavirus endemic to several West African countries
that causes Lassa fever (LF). LF is typically mild but it can cause severe disease …

New hosts of the Lassa virus

A Olayemi, D Cadar, NF Magassouba, A Obadare… - Scientific reports, 2016 - nature.com
Lassa virus (LASV) causes a deadly haemorrhagic fever in humans, killing several thousand
people in West Africa annually. For 40 years, the Natal multimammate rat, Mastomys …

Lassa fever diagnostics: past, present, and future

AN Happi, CT Happi, RJ Schoepp - Current opinion in virology, 2019 - Elsevier
Highlights•An orthogonal diagnostic system with multiple assays provides the greatest
confidence in a diagnostic result.•Lateral flow immunoassays (LFIs) can significantly reduce …

[HTML][HTML] Vaccine platforms for the prevention of Lassa fever

J Purushotham, T Lambe, SC Gilbert - Immunology Letters, 2019 - Elsevier
Lassa fever is an acute viral haemorrhagic illness caused by Lassa virus (LASV), which is
endemic throughout much of West Africa. The virus primarily circulates in the Mastomys …

[PDF][PDF] Lassa fever in West African sub-region: an overview

O Ogbu, E Ajuluchukwu, CJ Uneke - Journal of vector borne …, 2007 - mrcindia.org
Lassa fever is an acute viral zoonotic illness caused by Lassa virus, an arenavirus known to
be responsible for a severe haemorrhagic fever characterised by fever, muscle aches, sore …

Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development

HJ Hallam, S Hallam, SE Rodriguez, ADT Barrett… - NPJ vaccines, 2018 - nature.com
Lassa fever (LF) is a zoonotic disease associated with acute and potentially fatal
hemorrhagic illness caused by the Lassa virus (LASV), a member of the family Arenaviridae …

Lassa fever: epidemiology, clinical features, diagnosis, management and prevention

DA Asogun, S Günther, GO Akpede… - Infectious Disease …, 2019 - id.theclinics.com
Lassa fever, is an acute zoonotic disease of humans that is mainly endemic to West African
countries of Guinea, Liberia, Nigeria, and Sierra Leone. 1–3 Other countries such as Mali …

Lassa serology in natural populations of rodents and horizontal transmission

E Fichet-Calvet, B Becker-Ziaja, L Koivogui… - Vector-Borne and …, 2014 - liebertpub.com
Lassa virus causes hemorrhagic fever in West Africa. Previously, we demonstrated by PCR
screening that only the multimammate mouse, Mastomys natalensis, hosts Lassa virus in …

New opportunities for field research on the pathogenesis and treatment of Lassa fever

SH Khan, A Goba, M Chu, C Roth, T Healing, A Marx… - Antiviral research, 2008 - Elsevier
Unlike many viral hemorrhagic fevers (VHFs), Lassa fever (LF) is not a rare disease that
emerges only as sporadic cases or in outbreak form. Although surveillance is inadequate to …