OPFRs and BFRs induced A549 cell apoptosis by caspase-dependent mitochondrial pathway

X Yu, H Yin, H Peng, G Lu, Z Liu, Z Dang - Chemosphere, 2019 - Elsevier
Organophosphate flame retardants (OPFRs) and brominated flame retardants (BFRs) are
frequently detected in indoor environment at high levels, posing health risks to humans …

Organophosphate flame retardants induce oxidative stress and Chop/Caspase 3-related apoptosis via Sod1/p53/Map3k6/Fkbp5 in NCI-1975 cells

Y Meng, X Xu, D Niu, Y Xu, Y Qiu, Z Zhu… - Science of the Total …, 2022 - Elsevier
Organophosphate flame retardants (OPFRs) have been ubiquitously detected in dust and air
which could cause damage to human health through inhalation. Currently the understanding …

Tris (2-butoxyethyl) phosphate (TBEP): A flame retardant in solid waste display hepatotoxic and carcinogenic risks for humans

Q Saquib, AM Al-Salem, MA Siddiqui, SM Ansari… - Chemosphere, 2022 - Elsevier
Recent reports have confirmed that tris (2-butoxyethyl) phosphate (TBEP), an
organophosphorous flame retardants (OPFRs), profoundly detected in the dust from solid …

Toxicological effects of tris (2-chloropropyl) phosphate in human hepatic cells

F Li, L Wang, C Ji, H Wu, J Zhao, J Tang - Chemosphere, 2017 - Elsevier
Organophosphate flame retardants (OPFRs) are widely used as flame retardants which are
ubiquitous in various environment media. As many of OPFRs are toxic and persistent …

Aryl-phosphorus-containing flame retardants induce oxidative stress, the p53-dependent DNA damage response and mitochondrial impairment in A549 cells

S Yuan, Y Han, M Ma, K Rao, Z Wang, R Yang… - Environmental …, 2019 - Elsevier
Aryl phosphorus-containing flame retardants (aryl-PFRs) have been frequently detected with
increasingly used worldwide as one of alternatives for brominated flame retardants …

In vitro oxidative stress, mitochondrial impairment and G1 phase cell cycle arrest induced by alkyl-phosphorus-containing flame retardants

S Yuan, K Zhu, M Ma, X Zhu, K Rao, Z Wang - Chemosphere, 2020 - Elsevier
Phosphorus-containing flame retardants (PFRs) have been frequently detected in various
environmental samples at relatively high concentrations and are considered emerging …

The cytotoxicity of organophosphate flame retardants on HepG2, A549 and Caco-2 cells

J An, J Hu, Y Shang, Y Zhong, X Zhang… - … Science and Health …, 2016 - Taylor & Francis
In order to elucidate the cytotoxicity of organophosphate flame retardants (OPFRs), three
human in vitro models, namely the HepG2 hepatoma cells, the A549 lung cancer cells and …

The respiratory cytotoxicity of typical organophosphorus flame retardants on five different respiratory tract cells: Which are the most sensitive one?

J Chen, G Li, H Yu, H Liu, T An - Environmental Pollution, 2022 - Elsevier
Triphenyl phosphate (TPHP) is a frequently used flame retardant and indoor semi-volatile
pollutant exposing humans with endocrinal disrupting effects. However, its respiratory tract …

[HTML][HTML] Alkyl organophosphate flame retardants (OPFRs) induce lung inflammation and aggravate OVA-simulated asthmatic response via the NF-кB signaling …

Y Meng, X Xu, G Xie, Y Zhang, S Chen, Y Qiu… - Environment …, 2022 - Elsevier
Alkyl organophosphate flame retardants (OPFRs), tri-n-butyl phosphate (TnBP) and tris (2-
butoxyethyl) phosphate (TBOEP), are ubiquitously detected in indoor and outdoor …

Aryl-and alkyl-phosphorus-containing flame retardants induced mitochondrial impairment and cell death in Chinese hamster ovary (CHO-k1) cells

C Huang, N Li, S Yuan, X Ji, M Ma, K Rao… - Environmental Pollution, 2017 - Elsevier
Phosphorus-containing flame retardants (PFRs) are increasingly in demand worldwide as
replacements for brominated flame retardants (BFRs), but insufficient available toxicological …