Integrative analysis of the DNA methylome and transcriptome in uterine leiomyoma shows altered regulation of genes involved in metabolism, proliferation …

MC Carbajo‐García, A Corachán… - The Journal of …, 2022 - Wiley Online Library
Uterine leiomyomas (ULs) are the most common benign tumors in women of reproductive
age. Despite the high prevalence, tumor pathology remains unclear, which hampers the …

[HTML][HTML] Application of proteomics in cancer: recent trends and approaches for biomarkers discovery

YW Kwon, HS Jo, S Bae, Y Seo, P Song, M Song… - Frontiers in …, 2021 - frontiersin.org
Proteomics has become an important field in molecular sciences, as it provides valuable
information on the identity, expression levels, and modification of proteins. For example …

Approaching solid tumor heterogeneity on a cellular basis by tissue proteomics using laser capture microdissection and biological mass spectrometry

DJ Johann Jr, J Rodriguez-Canales… - Journal of proteome …, 2009 - ACS Publications
The purpose of this study was to examine solid tumor heterogeneity on a cellular basis using
tissue proteomics that relies on a functional relationship between Laser Capture …

The selected biomarker analysis in 5 types of uterine smooth muscle tumors

Q Zhang, MJ Kanis, J Ubago, D Liu, DM Scholtens… - Human pathology, 2018 - Elsevier
Uterine smooth muscle tumors (USMTs) consist of a group of histologically heterogeneous
and clinically diverse diseases ranging from malignant leiomyosarcoma (LMS) to benign …

Proteomic analysis of human endometrial tissues reveals the roles of PI3K/AKT/mTOR pathway and tumor angiogenesis molecules in the pathogenesis of endometrial …

Z Liu, Z Hong, P Qu - BioMed Research International, 2020 - Wiley Online Library
As one major gynecological malignancy, endometrial cancer (EC) has been widely studied
recently. However, its pathogenesis is still unclear to date. In this study, we identified …

[HTML][HTML] Proteomic and metabolomic profiling in soft tissue sarcomas

M Chadha, PH Huang - Current Treatment Options in Oncology, 2022 - Springer
Opinion statement Advances in proteomic and metabolomic technologies have accelerated
our understanding of multiple aspects of cancer biology across distinct tumour types. Here …

Identification of stage-specific breast markers using quantitative proteomics

S Shaheed, N Rustogi, A Scally, J Wilson… - Journal of proteome …, 2013 - ACS Publications
Matched healthy and diseased tissues from breast cancer patients were analyzed by
quantitative proteomics. By comparing proteomic profiles of fibroadenoma (benign tumors …

[PDF][PDF] Application of proteomics in cancer study

M Zamanian-Azodi, M Rezaei-Tavirani… - American Journal of …, 2013 - core.ac.uk
Cancer is one of the most malignant diseases in the world, accounting for 7.6 million deaths
(around 13% of all deaths) in 2008 based on WHO reports. Early detection of cancer is vital …

[HTML][HTML] Proteomic biomarkers for the detection of endometrial cancer

K Njoku, D Chiasserini, AD Whetton, EJ Crosbie - Cancers, 2019 - mdpi.com
Endometrial cancer is the leading gynaecological malignancy in the western world and its
incidence is rising in tandem with the global epidemic of obesity. Early diagnosis is key to …

[HTML][HTML] Proteomics approach highlights early changes in human fibroblasts-pancreatic ductal adenocarcinoma cells crosstalk

V Damiani, MC Cufaro, M Fucito, B Dufrusine, C Rossi… - Cells, 2022 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer mortality worldwide.
Non-specific symptoms, lack of biomarkers in the early stages, and drug resistance due to …