Adaptation of HepG2 cells to silver nanoparticles-induced stress is based on the pro-proliferative and anti-apoptotic changes in gene expression

K Brzóska, S Męczyńska-Wielgosz… - …, 2015 - academic.oup.com
Silver nanoparticles (AgNPs) are one of the most widely used nanomaterials due to their
antibacterial properties. Owing to the recent boost in the usage of AgNPs-containing …

Different responses of Caco-2 and MCF-7 cells to silver nanoparticles are based on highly similar mechanisms of action

M van der Zande, AK Undas, E Kramer… - …, 2016 - Taylor & Francis
The mode of action of silver nanoparticles (AgNPs) is suggested to be exerted through both
Ag+ and AgNP dependent mechanisms. Ingestion is one of the major NP exposure routes …

Silver nanoparticles induce endoplasmatic reticulum stress response in zebrafish

V Christen, M Capelle, K Fent - Toxicology and applied pharmacology, 2013 - Elsevier
Silver nanoparticles (AgNPs) find increasing applications, and therefore humans and the
environment are increasingly exposed to them. However, potential toxicological implications …

Silver nanoparticle‐induced oxidative stress, genotoxicity and apoptosis in cultured cells and animal tissues

S Kim, DY Ryu - Journal of applied toxicology, 2013 - Wiley Online Library
Silver nanoparticles (AgNPs) have emerged as an important class of nanomaterials for a
wide range of industrial and medical applications. However, the unique properties of AgNPs …

Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells

S Kim, JE Choi, J Choi, KH Chung, K Park, J Yi… - Toxicology in vitro, 2009 - Elsevier
Cytotoxicity induced by silver nanoparticles (AgNPs) and the role that oxidative stress plays
in this process were demonstrated in human hepatoma cells. Toxicity induced by silver …

Toxicity of silver nanoparticles as assessed by global gene expression analysis

L Xu, T Takemura, M Xu, N Hanagata - Materials Express, 2011 - ingentaconnect.com
Silver nanoparticles (Ag-NPs) showed a toxic effect on HeLa cells. For cells exposed to Ag-
NPs at a concentration of 20μg/ml for 24 h and 48 h, the number of viable cells decreased by …

In vivo DNA damaging and apoptotic potential of silver nanoparticles in Swiss albino mice

MA Al Gurabi, D Ali, S Alkahtani… - OncoTargets and therapy, 2015 - Taylor & Francis
Nanoparticles can potentially cause adverse effects on organs, tissue, cell levels, and
protein levels because of their physicochemical properties. Silver nanoparticles (AgNPs) are …

Multi-platform genotoxicity analysis of silver nanoparticles in the model cell line CHO-K1

X Jiang, R Foldbjerg, T Miclaus, L Wang, R Singh… - Toxicology letters, 2013 - Elsevier
Investigation of the genotoxic potential of nanomaterials is essential to evaluate if they pose
a cancer risk for exposed workers and consumers. The Chinese hamster ovary cell line CHO …

Silver nanoparticles induce toxicity in A549 cells via ROS-dependent and ROS-independent pathways

P Chairuangkitti, S Lawanprasert, S Roytrakul… - Toxicology in vitro, 2013 - Elsevier
Silver nanoparticles (AgNPs) are incorporated into a large number of consumer and medical
products. Several experiments have demonstrated that AgNPs can be toxic to the vital …

Adaptive regulations of Nrf2 alleviates silver nanoparticles-induced oxidative stress-related liver cells injury

M Guo, W Zhang, S Niu, M Shang, X Chang… - Chemico-Biological …, 2023 - Elsevier
Silver nanoparticles (AgNPs) are widely used in various fields such as industry, agriculture,
and medical care because of their excellent broad-spectrum antibacterial activity. However …