Animal models to test SARS-CoV-2 vaccines: which ones are in use and future expectations

G Gimenes Lima, AI Portilho, E De Gaspari - Pathogens, 2022 - mdpi.com
Since late 2019 and early 2020, with the emergence of the COVID-19 pandemic, scientists
are rushing to develop treatment and prevention methods to combat SARS-CoV-2. Among …

Current global vaccine and drug efforts against COVID-19: Pros and cons of bypassing animal trials

B Deb, H Shah, S Goel - Journal of biosciences, 2020 - Springer
COVID-19 has become one of the biggest health concern, along with huge economic
burden. With no clear remedies to treat the disease, doctors are repurposing drugs like …

COVID-19 animal models and vaccines: current landscape and future prospects

S Wang, L Li, F Yan, Y Gao, S Yang, X Xia - Vaccines, 2021 - mdpi.com
The worldwide pandemic of coronavirus disease 2019 (COVID-19) has become an
unprecedented challenge to global public health. With the intensification of the COVID-19 …

Mouse models in COVID-19 research: analyzing the adaptive immune response

S Clever, A Volz - Medical microbiology and immunology, 2023 - Springer
The emergence of SARS-CoV-2, the severe acute respiratory syndrome coronavirus type 2
causing the COVID-19 pandemic, resulted in a major necessity for scientific …

Are we paving the way to dig out of the “pandemic hole”? A narrative review on SARS-CoV-2 vaccination: from animal models to human immunization

G Tardiolo, P Brianti, D Sapienza, P dell'Utri, VD Dio… - Medical …, 2021 - mdpi.com
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new pathogen
agent causing the coronavirus infectious disease (COVID-19). This novel virus originated …

SARS-CoV-2: vaccines in the pandemic era

DD Li, QH Li - Military Medical Research, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has caused millions of infections and deaths …

Selection of animal models for COVID-19 research

S Kumar, PK Yadav, R Srinivasan, N Perumal - VirusDisease, 2020 - Springer
The researcher community across the globe is on a search for a promising animal model
that closely mimics the clinical manifestation of SARS-CoV-2. Though some developments …

An update on animal models for severe acute respiratory syndrome coronavirus 2 infection and countermeasure development

L Zhang, S Chen, W Zhang, H Yang, Y Jin… - Frontiers in …, 2021 - frontiersin.org
Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has become a pandemic since March 2020 and led to …

Potential SARS-CoV-2 vaccines: Concept, progress, and challenges

SA Hosseini, F Zahedipour, H Mirzaei… - International …, 2021 - Elsevier
Since September 2020, the world has had more than 28 million cases of coronavirus
disease 2019 (COVID-19). Many countries are facing a second wave of the COVID-19 …

COVID and animal trials: A systematic review

M Moothedath, M Muhamood, YS Bhosale… - Journal of Pharmacy …, 2021 - journals.lww.com
Extensive work is being done to form targeted drugs against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection; however, it is imperative to have a safe …