The presence of stem cells in the organ of Corti raises the hope of regeneration of
mammalian inner ear cells. However, little is known about the distribution of endogenous …

The adult mammalian cochlea lacks regenerative capacity, which is the main reason for the
permanence of hearing loss. Vestibular organs, in contrast, replace a small number of lost …

The mammalian inner ear has very limited ability to regenerate lost sensory hair cells. This
deficiency becomes apparent when hair cell loss leads to hearing loss as a result of either …

Stem cells in various mammalian organs retain the capacity to renew themselves and may
be able to restore damaged tissue. Their existence has been proven by genetic tracer …

Nonmammalian vertebrates regenerate lost sensory hair cells by means of asymmetric
division of supporting cells. Inner ear or lateral line supporting cells in birds, amphibians …

Basically stem cells have characteristics of multi-potency, differentiation into multiple tissue
types, and self-renew through proliferation. Recent advances in stem cell biology can make …

Background Previous reports showed the presence of limited numbers of stem cells in
neonatal murine cochlear sensory epithelia and these cells are progressively lost during the …

Genetic, noise-and drug-induced loss of hair cells in the mouse and human cochlea leads to
permanent hearing loss due to lack of regeneration of hair cells, which may be due to …

Conclusion: We characterized side population (SP) cells in the cochlear nucleus (CN).
Some genes of stem/progenitor markers in sorted SP cells were identified by microarray …

The low regenerative capacity of the hair cells of the mammalian inner ear is a major
obstacle for functional recovery following sensorineural hearing loss. A potential treatment is …