In the fields of biologically active materials and functional materials, fluorinated organic
materials are becoming a focus of significant interest. Over the past decade synthetic …

Methods for introducing fluorine into organic molecules are reviewed, with an emphasis on
preparation of compounds designed for biomedicinal applications. Electrophilic fluorination …

Drug candidates with one or more fluorines have become commonplace. The special nature
of fluorine imparts a variety of properties to certain medicines, including enhanced binding …

Introduction: The pivotal role that the element fluorine plays in modulating the properties of
bioactive molecules is reflected by the growth of its presence in approved drugs. In 1970 …

Synthetic fluorinated compounds are enormously useful in areas such as materials,
agrochemicals, pharmaceuticals and fine chemicals. While methods of electrophilic …

Contributed comment to the special Issue of Medicinal Chemistry Research marking the
retirement of Dr Nicholas Meanwell from Bristol Myers Squibb. The increasing incorporation …

Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates
reviews how the use of these techniques on compounds with already known and relevant …

Stereoselective halogenation reactions, in particular fluorinations, are not everyday's
chemistry despite the fundamental and still increasing significance of fluorinated molecules …

INTEREST IN ORGANOFLUORINE CHEMISTRY IS GROWING at a rapid pace. Fluorine as
a substituent can significantly affect the properties of molecular systems. Its high …

Fluorine has come to be recognized as a key element in materials science: in heat‐transfer
agents, liquid crystals, dyes, surfactants, plastics, elastomers, membranes, and other …