Tendon injuries are common and present a clinical challenge, as they often respond poorly
to treatment and result in long-term functional impairment. Inferior tendon healing responses …

Tendon-derived stem cell (TDSC) is a subpopulation of residing stem cells within the intact
tendon tissues, with the capacities of self-renewal, clonogenicity, and three-lineage …

Tendons are integral to our daily lives by allowing movement and locomotion but are
frequently injured, leading to patient discomfort and impaired mobility. Current clinical …

Background Tendon injury is a significant clinical problem due to poor healing and a high
reinjury rate; successful treatment is limited by our poor understanding of endogenous …

Background: Tendon is composed of connective tissue, is able to retract with high tensile
force, and plays a significant role in musculoskeletal motion. However, inappropriate …

Tendon/ligament injuries are very common in sports and other rigorous activities. Tendons
regenerate and repair slowly and inefficiently in vivo after injury. The limited ability of tendon …

Tendon tissues have limited healing capacity. The incidence of tendon injuries and the
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …

Tendon healing is complex to manage because of the limited regeneration capacity of
tendon tissue; stem cell-based tissue engineering approaches may provide alternative …

The management of tendon tissue injury presents a significant clinical challenge due to the
unique properties of tendons. Cell-based therapy provides a new alternative for …

Introduction Advances in tendon engineering with mesenchymal stem cells (MSCs) are
hindered by a need for cues to direct tenogenesis, and markers to assess tenogenic state …