Men with more advantaged socioeconomic position (SEP) have been observed to have
higher levels of testosterone. It is unclear whether these associations arise because …

Lower testosterone levels in men are observationally associated with worse health, but it is
unclear whether they contribute to well-established social gradients in health. Mendelian …

Background Testosterone levels are linked with diverse characteristics of human health, yet,
whether these associations reflect correlation or causation remains debated. Here, we …

Sex differences have been shown in laboratory biomarkers; however, the extent to which
this is due to genetics is unknown. In this study, we infer sex-specific genetic parameters …

Testosterone concentrations in men are associated with cardiovascular morbidity,
osteoporosis, and mortality and are affected by age, smoking, and obesity. Because of …

Context Obesity in men is associated with low serum testosterone and both are associated
with several diseases and increased mortality. Objectives Examine the direction and …

Testosterone supplementation is commonly used for its effects on sexual function, bone
health and body composition, yet its effects on disease outcomes are unknown. To better …

Background Observationally lower testosterone is associated with an unhealthier
cardiovascular (CVD) risk profile, but this association is open to confounding and reverse …

Background Testosterone is an essential sex hormone that plays a vital role in the overall
health and development of males. It is well known that obesity decreases testosterone …

Objective Epidemiological and clinical studies have highlighted important roles for sex
hormones in the regulation of fat distribution and systemic metabolism. We investigated the …