Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank
Objective To determine whether endogenous testosterone has a causal role in
thromboembolism, heart failure, and myocardial infarction. Design Two sample mendelian …
thromboembolism, heart failure, and myocardial infarction. Design Two sample mendelian …
Association between testosterone levels and bone mineral density in females aged 40–60 years from NHANES 2011–2016
H Zhang, K Ma, RM Li, JN Li, SF Gao, LN Ma - Scientific Reports, 2022 - nature.com
Growing evidence indicates that testosterone is a conspicuous marker for assessing male
bone mineral density (BMD). However, research regarding testosterone levels and BMD is …
bone mineral density (BMD). However, research regarding testosterone levels and BMD is …
Higher serum testosterone level was associated with a lower risk of prediabetes in US adults: findings from nationally representative data
Low testosterone may be a novel risk factor for prediabetes. We assessed the associations
between prediabetes and total serum testosterone (TT), and whether the associations were …
between prediabetes and total serum testosterone (TT), and whether the associations were …
Assessment of gene‐by‐sex interaction effect on bone mineral density
Sexual dimorphism in various bone phenotypes, including bone mineral density (BMD), is
widely observed; however, the extent to which genes explain these sex differences is …
widely observed; however, the extent to which genes explain these sex differences is …
Developing a transcriptomic framework for testing testosterone-mediated handicap hypotheses
DJ Newhouse, BJ Vernasco - General and Comparative Endocrinology, 2020 - Elsevier
Sexually selected traits are hypothesized to be honest signals of individual quality due to the
costs associated with their maintenance, development, and/or production. Testosterone, a …
costs associated with their maintenance, development, and/or production. Testosterone, a …
High serum testosterone is associated with reduced risk of cardiovascular events in elderly men: the MrOS (Osteoporotic Fractures in Men) study in Sweden
Objectives: We tested the hypothesis that serum total testosterone and sex hormone–
binding globulin (SHBG) levels predict cardiovascular (CV) events in community-dwelling …
binding globulin (SHBG) levels predict cardiovascular (CV) events in community-dwelling …
Low testosterone concentrations in men contribute to the gender gap in cardiovascular morbidity and mortality
BACKGROUND: Across the industrialized world, men experience an earlier onset of
cardiovascular disease (CVD) and a life expectancy 5 to 10 years shorter than women. Low …
cardiovascular disease (CVD) and a life expectancy 5 to 10 years shorter than women. Low …
Racial variation in sex steroid hormone concentration in black and white men: a meta‐analysis
A Richard, S Rohrmann, L Zhang, M Eichholzer… - …, 2014 - Wiley Online Library
Sex steroid hormones are associated with chronic diseases and mortality with risk
associations that differ between racial and ethnic groups. However, it is currently unclear …
associations that differ between racial and ethnic groups. However, it is currently unclear …
Mendelian randomisation analysis provides no evidence for a relationship between adult height and testicular cancer risk
Observational studies have suggested anthropometric traits, particularly increased height
are associated with an elevated risk of testicular cancer (testicular germ cell tumour) …
are associated with an elevated risk of testicular cancer (testicular germ cell tumour) …
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
Given the anthropometric differences between men and women and previous evidence of
sex-difference in genetic effects, we conducted a genome-wide search for sexually …
sex-difference in genetic effects, we conducted a genome-wide search for sexually …