[HTML][HTML] Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

JC Randall, TW Winkler, Z Kutalik, SI Berndt… - PLoS …, 2013 - journals.plos.org
Given the anthropometric differences between men and women and previous evidence of
sex-difference in genetic effects, we conducted a genome-wide search for sexually …

Mendelian randomisation analysis provides no evidence for a relationship between adult height and testicular cancer risk

M Levy, D Hall, A Sud, P Law, K Litchfield… - …, 2017 - Wiley Online Library
Observational studies have suggested anthropometric traits, particularly increased height
are associated with an elevated risk of testicular cancer (testicular germ cell tumour) …

[HTML][HTML] Predictive value of serum testosterone for type 2 diabetes risk assessment in men

E Atlantis, P Fahey, S Martin, P O'Loughlin… - BMC Endocrine …, 2016 - Springer
Background Effective prevention of type 2 diabetes (T2D) requires early identification of high-
risk individuals who might benefit from intervention. We sought to determine whether low …

Testosterone: Relationships with Metabolic Disorders in Men—An Observational Study from SPECT‐China

J Cheng, B Han, Q Li, F Xia, H Zhai… - International journal …, 2017 - Wiley Online Library
Background. The strength of associations between total testosterone (TT) and metabolic
parameters may vary in different nature of population structure; however, no study has ever …

[HTML][HTML] Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1

CDJ Kusters, KC Paul, AT Lu, L Ferruci, BR Ritz… - GeroScience, 2024 - Springer
Sex hormones are hypothesized to drive sex-specific health disparities. Here, we study the
association between sex steroid hormones and DNA methylation-based (DNAm) biomarkers …

Commentary: testosterone and the metabolic syndrome: cause or consequence?

DA Rees, CM Dayan - International journal of epidemiology, 2011 - academic.oup.com
TESTOSTERONE AND THE METABOLIC SYNDROME 207 of the syndrome conveys a
significantly increased risk of type 2 diabetes (T2DM) and cardiovascular disease, hence …

Metabolic profiles of socio-economic position: a multi-cohort analysis

O Robinson, AR Carter, M Ala-Korpela… - International Journal …, 2021 - academic.oup.com
Background Low socio-economic position (SEP) is a risk factor for multiple health outcomes,
but its molecular imprints in the body remain unclear. Methods We examined SEP as a …

[HTML][HTML] Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations

BP Prins, KB Kuchenbaecker, Y Bao, M Smart… - Scientific reports, 2017 - nature.com
Serum biomarker levels are associated with the risk of complex diseases. Here, we aimed to
gain insights into the genetic architecture of biomarker traits which can reflect health status …

[HTML][HTML] Testosterone level reduction increases the 10-year risk of cardiovascular diseases: A retrospective cohort study in a taiwanese young male population

HH Yang, SK Tu, HH Chen, CL Hung… - Frontiers in …, 2022 - frontiersin.org
Low testosterone levels are associated with increased risk of cardiovascular disease;
however, most previous studies assessed the relationship of testosterone levels with a …

[HTML][HTML] Percent body fat was negatively correlated with Testosterone levels in male

H Ma, J Sun, X Wu, J Mao, Q Han - Plos one, 2024 - journals.plos.org
Background Lower testosterone levels in men have been consistently associated with
metabolic abnormalities, particularly obesity. This study aims to investigate the relationship …