Dapagliflozin and kidney outcomes in patients with heart failure with mildly reduced or preserved ejection fraction: a prespecified analysis of the DELIVER randomized …

FR Mc Causland, BL Claggett, M Vaduganathan… - JAMA …, 2023 - jamanetwork.com
Importance Sodium-glucose cotransporter 2 inhibitors are known to reduce heart failure
events and slow progression of kidney disease among patients with heart failure and a …

Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF

PS Jhund, SD Solomon, KF Docherty, HJL Heerspink… - Circulation, 2021 - Am Heart Assoc
Background: Many patients with heart failure and reduced ejection fraction (HFrEF) have
chronic kidney disease that complicates pharmacological management and is associated …

Dapagliflozin and diuretic utilization in heart failure with mildly reduced or preserved ejection fraction: the DELIVER trial

S Chatur, M Vaduganathan, B Claggett… - European heart …, 2023 - academic.oup.com
Aims Dapagliflozin reduced the combined risk of worsening heart failure or cardiovascular
death among patients with heart failure with mildly reduced or preserved ejection fraction. In …

Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER

PS Jhund, T Kondo, JH Butt, KF Docherty… - Nature medicine, 2022 - nature.com
Whether the sodium–glucose cotransporter 2 inhibitor dapagliflozin reduces the risk of a
range of morbidity and mortality outcomes in patients with heart failure regardless of ejection …

[HTML][HTML] Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction

SD Solomon, JJV McMurray, B Claggett… - … England Journal of …, 2022 - Mass Medical Soc
Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of
hospitalization for heart failure and cardiovascular death among patients with chronic heart …

Time to clinical benefit of dapagliflozin in patients with heart failure with mildly reduced or preserved ejection fraction: a prespecified secondary analysis of the …

M Vaduganathan, BL Claggett, P Jhund… - JAMA …, 2022 - jamanetwork.com
Importance Dapagliflozin was recently shown to reduce cardiovascular death or worsening
heart failure (HF) events in patients with HF with mildly reduced or preserved ejection …

Time to clinical benefit of dapagliflozin and significance of prior heart failure hospitalization in patients with heart failure with reduced ejection fraction

DD Berg, PS Jhund, KF Docherty, SA Murphy… - JAMA …, 2021 - jamanetwork.com
Importance Dapagliflozin has been shown to reduce the risk of cardiovascular death or
worsening heart failure (HF) in patients with chronic HF and reduced ejection fraction …

Initial decline (dip) in estimated glomerular filtration rate after initiation of dapagliflozin in patients with heart failure and reduced ejection fraction: insights from DAPA …

C Adamson, KF Docherty, HJL Heerspink, RA de Boer… - Circulation, 2022 - Am Heart Assoc
Background: In a post hoc analysis, the frequency of occurrence of an early decline (dip) in
estimated glomerular filtration rate (eGFR) after initiation of dapagliflozin and its association …

Dapagliflozin effects on biomarkers, symptoms, and functional status in patients with heart failure with reduced ejection fraction: the DEFINE-HF trial

ME Nassif, SL Windsor, F Tang, Y Khariton, M Husain… - Circulation, 2019 - Am Heart Assoc
Background: Outcome trials in patients with type 2 diabetes mellitus have demonstrated
reduced hospitalizations for heart failure (HF) with sodium-glucose co-transporter-2 …

A trial to evaluate the effect of the sodium–glucose co‐transporter 2 inhibitor dapagliflozin on morbidity and mortality in patients with heart failure and reduced left …

JJV McMurray, DL DeMets, SE Inzucchi… - European journal of …, 2019 - Wiley Online Library
Background Sodium–glucose co‐transporter 2 (SGLT2) inhibitors have been shown to
reduce the risk of incident heart failure hospitalization in individuals with type 2 diabetes …