Maternal and genetic factors determine early life telomere length

M Asghar, S Bensch, M Tarka… - … of the Royal …, 2015 - royalsocietypublishing.org
In a broad range of species—including humans—it has been demonstrated that telomere
length declines throughout life and that it may be involved in cell and organismal …

Heritability of telomere variation: it is all about the environment!

HL Dugdale, DS Richardson - … Transactions of the …, 2018 - royalsocietypublishing.org
Individual differences in telomere length have been linked to survival and senescence.
Understanding the heritability of telomere length can provide important insight into individual …

Large-scale parent–child comparison confirms a strong paternal influence on telomere length

K Nordfjäll, U Svenson, KF Norrback… - European Journal of …, 2010 - nature.com
Telomere length is documented to have a hereditary component, and both paternal and X-
linked inheritance have been proposed. We investigated blood cell telomere length in 962 …

Telomere length inheritance and aging

D Kappei, JA Londoño-Vallejo - Mechanisms of ageing and development, 2008 - Elsevier
Telomere shortening accompanies human aging, and premature aging syndromes are often
associated with short telomeres. These two observations are central to the hypothesis that …

Telomere length predicts survival independent of genetic influences

SL Bakaysa, LA Mucci, PE Slagboom, DI Boomsma… - Aging cell, 2007 - Wiley Online Library
Telomeres prevent the loss of coding genetic material during chromosomal replication.
Previous research suggests that shorter telomere length may be associated with lower …

Telomeres and life histories: the long and the short of it

P Monaghan - Annals of the New York Academy of Sciences, 2010 - Wiley Online Library
Telomeres are repetitive DNA sequences at the ends of eukaryote chromosomes. Telomere
loss limits the number of times cells can divide and is intimately involved in cell loss and …

The relative lengths of individual telomeres are defined in the zygote and strictly maintained during life

J Graakjaer, L Pascoe, H Der‐Sarkissian… - Aging cell, 2004 - Wiley Online Library
Previous studies have indicated that average telomere length is partly inherited (Slagboom
et al., 1994; Rufer et al., 1999) and that there is an inherited telomere pattern in each cell …

Telomere heritability and parental age at conception effects in a wild avian population

AM Sparks, LG Spurgin, M van der Velde… - Molecular …, 2022 - Wiley Online Library
Individual variation in telomere length is predictive of health and mortality risk across a
range of species. However, the relative influence of environmental and genetic variation on …

Paternal age is positively linked to telomere length of children

BM Unryn, LS Cook, KT Riabowol - Aging cell, 2005 - Wiley Online Library
Telomere length is linked to age‐associated diseases, with shorter telomeres in blood
associated with an increased probability of mortality from infection or heart disease. Little is …

Genetic, parental and lifestyle factors influence telomere length

S Andreu-Sánchez, G Aubert… - Communications …, 2022 - nature.com
The average length of telomere repeats (TL) declines with age and is considered to be a
marker of biological ageing. Here, we measured TL in six blood cell types from 1046 …