Inflammatory cytokine: IL-17A signaling pathway in patients present with COVID-19 and current treatment strategy

T Shibabaw - Journal of inflammation research, 2020 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) is a globally communicable public health
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV-2) …

Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections

A Bénard, A Jacobsen, M Brunner, C Krautz… - Nature …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide health
threat. In a prospective multicentric study, we identify IL-3 as an independent prognostic …

Interleukin 6, soluble interleukin 2 receptor alpha (CD25), monocyte colony-stimulating factor, and hepatocyte growth factor linked with systemic hyperinflammation …

L Quartuccio, M Fabris, A Sonaglia, M Peghin… - Cytokine, 2021 - Elsevier
Background Patients infected by SARS-CoV-2 can develop interstitial pneumonia, requiring
hospitalisation or mechanical ventilation. Increased levels of inflammatory biomarkers are …

Expression of IFN-Gamma is significantly reduced during severity of covid-19 infection in hospitalized patients

S Mansoor, AR Butt, A Bibi, S Mushtaq, I Ullah… - Plos one, 2023 - journals.plos.org
Cytokines play an important role in SARS-CoV-2 infection progression and severity. A
number of inflammatory cytokines have been directly associated with disease severity …

A potential role of interleukin 10 in COVID-19 pathogenesis

L Lu, H Zhang, DJ Dauphars, YW He - Trends in Immunology, 2021 - cell.com
A unique feature of the cytokine storm in coronavirus disease 2019 (COVID-19) is the
dramatic elevation of interleukin 10 (IL-10). This was thought to be a negative feedback …

COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
The recent novel coronavirus disease (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is seeing a rapid increase in infected …

COVID-19: in the eye of the cytokine storm

R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
The dysregulated release of cytokines has been identified as one of the key factors behind
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …

Critical determinants of cytokine storm and type I interferon response in COVID-19 pathogenesis

S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19), a rapidly evolving pandemic worldwide with at least 68 million …

[HTML][HTML] The role of Interleukin 6 inhibitors in therapy of severe COVID-19

E Nasonov, M Samsonov - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cytokine storm syndrome (CSS) is a severe complication of inflammatory immune diseases
or treatment of malignancies; it may also appear during the progression of COVID-19. CSS …

Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

Y Jamilloux, T Henry, A Belot, S Viel, M Fauter… - Autoimmunity …, 2020 - Elsevier
The coronavirus disease-19 pandemic (COVID-19), which appeared in China in December
2019 and rapidly spread throughout the world, has forced clinicians and scientists to take up …