Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK

C Park, CY Jin, GY Kim, IW Choi, TK Kwon… - Toxicology and applied …, 2008 - Elsevier
Esculetin is a phenolic compound that is found in various natural plant products and induces
apoptosis in several types of human cancer cells. However, the underlying mechanisms of …

[HTML][HTML] Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species‑mediated mitochondrial death pathway

HH Lee, C Park, JW Jeong, MJ Kim… - International …, 2013 - spandidos-publications.com
Cordycepin is the main functional component of Cordyceps militaris, which has been widely
used in oriental traditional medicine. This compound has been shown to possess many …

Neem oil limonoids induces p53-independent apoptosis and autophagy

P Srivastava, N Yadav, R Lella, A Schneider… - …, 2012 - academic.oup.com
Azadirachta indica, commonly known as neem, has a wide range of medicinal properties.
Neem extracts and its purified products have been examined for induction of apoptosis in …

Evodiamine prevents glioma growth, induces glioblastoma cell apoptosis and cell cycle arrest through JNK activation

WS Wu, CC Chien, KH Liu, YC Chen… - The American Journal of …, 2017 - World Scientific
Evodiamine (EVO) is an active medicinal compound derived from the traditional herbal
medicine Evodia rutaecarpa. It has been reported that evodiamine has several beneficial …

Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma

HZ Lee, SL Hsu, MC Liu, CH Wu - European journal of pharmacology, 2001 - Elsevier
Aloe-emodin (1, 8-dihydroxy-3-(hydroxymethyl)-anthraquinone) is an active component from
the root and rhizome of Rheum palmatum. The study investigated the effects and …

Quercetin induces the apoptosis of human ovarian carcinoma cells by upregulating the expression of microRNA‑145

J Zhou, J Gong, C Ding, G Chen - Molecular medicine …, 2015 - spandidos-publications.com
Ovarian cancer is one of the most malignant types of cancer of the female human
reproductive track, posing a severe threat to the health of the female population. Numerous …

Deoxyelephantopin from Elephantopus scaber L. induces cell-cycle arrest and apoptosis in the human nasopharyngeal cancer CNE cells

M Su, HY Chung, Y Li - Biochemical and biophysical research …, 2011 - Elsevier
Deoxyelephantopin (ESD), a naturally occurring sesquiterpene lactone present in the
Chinese medicinal herb, Elephantopus scaber L. exerted anticancer effects on various …

The distinct mechanisms of the antitumor activity of emodin in different types of cancer

WT Wei, SZ Lin, DL Liu, ZH Wang - Oncology reports, 2013 - spandidos-publications.com
Emodin, a tyrosine kinase inhibitor, is a natural anthraquinone derivative found in the roots
and rhizomes of numerous plants. The inhibitory effect of emodin on mammalian cell cycle …

Apigenin induced apoptosis through p53-dependent pathway in human cervical carcinoma cells

PW Zheng, LC Chiang, CC Lin - Life sciences, 2005 - Elsevier
Apigenin is a widely distributed plant flavonoid and was proposed as an antitumor agent. In
this study, we reported for the first time that apigenin inhibited the growth of human cervical …

Oridonin induces apoptosis of HeLa cells via altering expression of Bcl-2/Bax and activating caspase-3/ICAD pathway.

CL Zhang, LJ Wu, S Tashiro, S Onodera… - Acta Pharmacologica …, 2004 - europepmc.org
Methods Viability of oridonin-induced HeLa cells was measured by MTT assay. Apoptotic
cells with condensed nuclei were visualized by phase contrast microscopy. Nucleosomal …