Association between nirmatrelvir plus ritonavir and the outcomes of non-hospitalized obese patients with COVID-19

JY Wu, MY Liu, TH Liu, MH Chuang, WH Hsu… - International Journal of …, 2023 - Elsevier
Objective To investigate the association between nirmatrelvir plus ritonavir (NMV-r) and the
outcomes of non-hospitalized obese patients with coronavirus disease 2019 (COVID-19) …

[HTML][HTML] Is azvudine comparable to nirmatrelvir-ritonavir in real-world efficacy and safety for hospitalized patients with COVID-19? A retrospective cohort study

Q Zhao, B Zheng, B Han, P Feng, Z Xia, H Jiang… - Infectious Diseases and …, 2023 - Springer
Introduction Azvudine and nirmatrelvir-ritonavir are more extensively used to treat COVID-19
in China due to their earlier approval by the National Medical Products Administration …

Oral nirmatrelvir and ritonavir for coronavirus disease 2019 in vaccinated, nonhospitalized adults aged 18–50 years

JS Faust, A Kumar, J Shah, S Khadke… - Clinical Infectious …, 2023 - academic.oup.com
Background The effects of nirmatrelvir/ritonavir (NMV/r [Paxlovid]) on coronavirus disease
2019 (COVID-19) outcomes in younger vaccinated adults are unclear. The objective of this …

[HTML][HTML] Viral burden rebound in hospitalised patients with COVID-19 receiving oral antivirals in Hong Kong: a population-wide retrospective cohort study

CKH Wong, KTK Lau, ICH Au, EHY Lau… - The Lancet infectious …, 2023 - thelancet.com
Background Viral rebound after nirmatrelvir–ritonavir treatment has implications for the
clinical management and isolation of patients with COVID-19. We evaluated an unselected …

Association of Nirmatrelvir/Ritonavir Treatment with Long COVID Symptoms in an Online Cohort of Non-Hospitalized Individuals Experiencing Breakthrough SARS …

MS Durstenfeld, MJ Peluso, F Lin, ND Peyser, C Isasi… - medRxiv, 2023 - medrxiv.org
Background Oral nirmatrelvir/ritonavir is a treatment for COVID-19, but whether treatment
during the acute phase reduces the risk of developing Long COVID is unknown. Methods …

An open, prospective cohort study of VV116 in Chinese participants infected with SARS-CoV-2 omicron variants

Y Shen, J Ai, N Lin, H Zhang, Y Li, H Wang… - Emerging microbes & …, 2022 - Taylor & Francis
Omicron variant of SARS-CoV-2 has become the predominant variant worldwide. VV116 is
an oral drug with robust anti-SARS-CoV-2 efficacy in preclinical studies. We conducted an …

Effectiveness of molnupiravir in high-risk patients: a propensity score matched analysis

R Najjar-Debbiny, N Gronich, G Weber… - Clinical infectious …, 2023 - academic.oup.com
Background Molnupiravir was granted emergency use authorization for the treatment of mild
to moderate coronavirus disease 2019 (COVID-19). In this study, we used population-based …

Post-acute hospitalization and mortality of nirmatrelvir plus ritonavir for COVID-19 survivors

WH Hsu, YW Tsai, JY Wu, TH Liu… - Journal of Infection, 2023 - journalofinfection.com
We read with interest the retrospective observational study investigating the short-term effect
of oral anti-viral agents on United States Veterans aged 65 years and older who were at …

Effectiveness of molnupiravir and nirmatrelvir–ritonavir in hospitalized patients with COVID-19: a target trial emulation study

EYF Wan, VKC Yan, AHY Mok, B Wang… - Annals of internal …, 2023 - acpjournals.org
Background: Whether hospitalized patients benefit from COVID-19 oral antivirals is
uncertain. Objective: To examine the real-world effectiveness of molnupiravir and …

Etiology, clinical features, infection control and therapy of SARS-CoV-2 Omicron variant

YU Yue-Cheng, S Yong - Jie Fang Jun Yi Xue Za Zhi, 2022 - search.proquest.com
The Omicron variant of SARS-CoV-2 is a new variant of concern after Alpha, Beta, Gamma
and Delta variants. The amino acid mutations in the viral antigens, especially in the receptor …