There has been substantial progress in understanding the genetics of schizophrenia over
the past 15 years. This has revealed a highly polygenic condition with the majority of the …

Schizophrenia is a major debilitating psychiatric disorder affecting∼ 1% of the population
worldwide. A tremendous amount of effort has been expended in the last two decades to …

Identifying genes for schizophrenia through classical genetic approaches has proven
arduous. Here, we present a comprehensive convergent analysis that translationally …

Abstract Purpose of Review This is an era where we have significantly advanced the
understanding of the genetic architecture of schizophrenia. In this review, we consider how …

Genome-wide association studies (GWAS) have identified over 100 risk loci for
schizophrenia, but the causal mechanisms remain largely unknown. We performed a …

The desire to understand the pathophysiology of schizophrenia has inspired an explosion in
research over the past decade. This review highlights some key studies that have led to …

Despite large-scale genome-wide association studies (GWAS), the underlying genes for
schizophrenia are largely unknown. Additional approaches are therefore required to identify …

Over 100 genetic loci harbor schizophrenia-associated variants, yet how these variants
confer liability is uncertain. The CommonMind Consortium sequenced RNA from …

Schizophrenia is a severe psychiatric disorder with considerable morbidity and mortality.
Although the past two decades have seen limited improvement in the treatment of …

Recent genome-wide association studies (GWAS) have identified multiple risk loci that show
strong associations with schizophrenia. However, pinpointing the potential causal genes at …