[PDF][PDF] Novel findings from CNVs implicate inhibitory and excitatory signaling complexes in schizophrenia
AJ Pocklington, E Rees, JTR Walters, J Han… - Neuron, 2015 - cell.com
We sought to obtain novel insights into schizophrenia pathogenesis by exploiting the
association between the disorder and chromosomal copy number (CNV) burden. We …
association between the disorder and chromosomal copy number (CNV) burden. We …
The schizophrenia risk gene ZNF804A: clinical associations, biological mechanisms and neuronal functions
H Chang, X Xiao, M Li - Molecular psychiatry, 2017 - nature.com
ZNF804A (zinc-finger protein 804A) has been recognized as a schizophrenia risk gene
across multiple world populations. Its intronic single-nucleotide polymorphism (SNP) …
across multiple world populations. Its intronic single-nucleotide polymorphism (SNP) …
A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples
P Roussos, P Katsel, KL Davis, LJ Siever… - Archives of general …, 2012 - jamanetwork.com
Context Schizophrenia is a common, highly heritable, neurodevelopmental mental illness,
characterized by genetic heterogeneity. Objective To identify abnormalities in the …
characterized by genetic heterogeneity. Objective To identify abnormalities in the …
[HTML][HTML] Schizophrenia: susceptibility genes and oligodendroglial and myelin related abnormalities
P Roussos, V Haroutunian - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Given that the genetic risk for schizophrenia is highly polygenic and the effect sizes, even for
rare or de novo events, are modest at best, it has been suggested that multiple biological …
rare or de novo events, are modest at best, it has been suggested that multiple biological …
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk
INTRODUCTION Chromosomal conformations, topologically associated chromatin domains
(TADs) assembling in nested fashion across hundreds of kilobases, and other “three …
(TADs) assembling in nested fashion across hundreds of kilobases, and other “three …
Functional connectome-wide associations of schizophrenia polygenic risk
Schizophrenia is a highly heritable mental disorder characterized by functional
dysconnectivity across the brain. However, the relationships between polygenic risk factors …
dysconnectivity across the brain. However, the relationships between polygenic risk factors …