Background The protective immunity against omicron following a BNT162b2 Pfizer booster
dose among elderly individuals (ie, those aged> 65 years) is not well characterised …

Background The present study aimed to evaluate the persistent immunogenicity offered by a
third dose of BNT162b2 against Delta and Omicron variants, in nursing home (NH) …

Background SARS-CoV-2 vaccination is the most effective strategy to protect older residents
of long-term care facilities (LTCF) against severe COVID-19, but primary vaccine responses …

We investigated whether peripheral blood levels of SARS‐CoV‐2 Spike (S) receptor binding
domain antibodies (anti‐RBD), neutralizing antibodies (NtAb) targeting Omicron S, and S …

Background Nursing home (NH) residents have borne a disproportionate share of SARS-
CoV-2 morbidity and mortality. Vaccines have limited hospitalisation and death from earlier …

Immunosenescence may impact the functionality and breadth of vaccine-elicited humoral
immune responses. The ability of sera to neutralize the SARS-CoV-2 spike protein (S) from …

Background Duration of post‐vaccination protection against COVID‐19 in nursing home
(NH) residents is a critical issue. The objective of this study was to estimate the duration of …

SARS-CoV-2 variants threaten the effectiveness of tools we have developed to mitigate
against serious COVID-19. This is especially true in clinically vulnerable sections of society …

Background. Several Canadian provinces are extending the interval between COVID-19
vaccine doses to increase population vaccine coverage more rapidly. However …

Background Vaccination reduces COVID-19-related hospitalization among older adults.
However, how SARS-CoV-2 infection and vaccine regimens affect vaccine-elicited immunity …