Manipulation and extraction of genomic DNA from cell lysate by functionalized magnetic particles for lab on a chip applications

SW Yeung, IM Hsing - Biosensors and Bioelectronics, 2006 - Elsevier
A novel approach for extracting living cells' genomic DNA materials utilizing functionalized
magnetic particles (MPs) is reported in this investigation. This strategy is amenable to …

Rapid enrichment of leucocytes and genomic DNA from blood based on bifunctional core–shell magnetic nanoparticles

X Xie, X Nie, B Yu, X Zhang - Journal of magnetism and magnetic materials, 2007 - Elsevier
A series of protocols are proposed to extract genomic DNA from whole blood at different
scales using carboxyl-functionalized magnetic nanoparticles as solid-phase absorbents …

Magnetic particles for in vitro molecular diagnosis: From sample preparation to integration into microsystems

T Tangchaikeeree, D Polpanich, A Elaissari… - Colloids and Surfaces B …, 2017 - Elsevier
Colloidal magnetic particles (MPs) have been developed in association with molecular
diagnosis for several decades. MPs have the great advantage of easy manipulation using a …

On-chip bioanalysis with magnetic particles

N Pamme - Current opinion in chemical biology, 2012 - Elsevier
Magnetic particles can combine two very selective processes in bioanalysis: the specific
binding of analytes to the particle surface based on molecular recognition and the specific …

Rapid, multistep on-chip DNA hybridisation in continuous flow on magnetic particles

M Vojtíšek, A Iles, N Pamme - Biosensors and Bioelectronics, 2010 - Elsevier
DNA hybridisation is an important tool for bioanalytical research and clinical diagnostics;
conventional methods, however, require long incubation times and numerous washing …

Topography-assisted electromagnetic platform for blood-to-PCR in a droplet

CH Chiou, DJ Shin, Y Zhang, TH Wang - Biosensors and Bioelectronics, 2013 - Elsevier
This paper presents an electromagnetically actuated platform for automated sample
preparation and detection of nucleic acids. The proposed platform integrates nucleic acid …

A magnetic bead-based DNA extraction and purification microfluidic device

SM Azimi, G Nixon, J Ahern… - Microfluidics and …, 2011 - Springer
This article introduces a novel magnetic bead-based DNA extraction and purification device
using active magnetic mixing approach. Mixing and separation steps are performed using …

Novel 3D-printed microfluidic magnetic platform for rapid DNA isolation

G Kibar, B Sarıarslan, S Doğanay, G Yıldız… - Analytical …, 2024 - ACS Publications
This study presents a novel miniaturized device as a 3D-printed microfluidic magnetic
platform specifically designed to manipulate magnetic microparticles in a microfluidic chip …

Magnetic and gold-coated magnetic nanoparticles as a DNA sensor

GK Kouassi, J Irudayaraj - Analytical Chemistry, 2006 - ACS Publications
In this study, we report the chemical synthesis and functionalization of magnetic and gold-
coated magnetic nanoparticles and the immobilization of single-stranded biotinylated …

Sensitive detection of bacterial DNA by magnetic nanoparticles

J Göransson, T Zardán Gómez De La Torre… - Analytical …, 2010 - ACS Publications
This work presents sensitive detection of bacterial genomic DNA using a magnetic
nanoparticle-based substrate-free method. For the first time, such a method is employed for …