Antagonism of type I interferon by severe acute respiratory syndrome coronavirus 2
The coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), warranting urgent study of the molecular …
syndrome coronavirus 2 (SARS-CoV-2), warranting urgent study of the molecular …
[HTML][HTML] Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents
Abstract Background Coronavirus disease 2019 (COVID-19) is caused by Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, previously named 2019-nCov), a novel …
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, previously named 2019-nCov), a novel …
Epithelial response to IFN‐γ promotes SARS‐CoV‐2 infection
J Heuberger, J Trimpert, D Vladimirova… - EMBO molecular …, 2021 - embopress.org
Abstract SARS‐CoV‐2, the agent that causes COVID‐19, invades epithelial cells, including
those of the respiratory and gastrointestinal mucosa, using angiotensin‐converting enzyme …
those of the respiratory and gastrointestinal mucosa, using angiotensin‐converting enzyme …
[HTML][HTML] The COVID-19 cytokine storm; what we know so far
D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract …
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract …
[HTML][HTML] Heightened circulating interferon-inducible chemokines, and activated pro-cytolytic Th1-cell phenotype features Covid-19 aggravation in the second week of …
C Tincati, ES Cannizzo, M Giacomelli… - Frontiers in …, 2020 - frontiersin.org
Covid-19 features a delayed onset of critical illness occurring approximately one week from
the beginning of symptoms, which corresponds to the bridging of innate and adaptive …
the beginning of symptoms, which corresponds to the bridging of innate and adaptive …
[HTML][HTML] COVID-19: in the eye of the cytokine storm
R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
The dysregulated release of cytokines has been identified as one of the key factors behind
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …
[HTML][HTML] Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity
Host immunity to infection with SARS-CoV-2 is highly variable, dictating diverse clinical
outcomes ranging from asymptomatic to severe disease and death. We previously reported …
outcomes ranging from asymptomatic to severe disease and death. We previously reported …
[HTML][HTML] Characterization of SARS-CoV-2 evasion: interferon pathway and therapeutic options
M Znaidia, C Demeret, S van der Werf, AV Komarova - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the
current COVID-19 pandemic. SARS-CoV-2 is characterized by an important capacity to …
current COVID-19 pandemic. SARS-CoV-2 is characterized by an important capacity to …
Cytokine storm induced by SARS-CoV-2
P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …
The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection
A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …