[HTML][HTML] Blood interferon-α levels and severity, outcomes, and inflammatory profiles in hospitalized COVID-19 patients
Background: Deficient interferon responses have been proposed as one of the relevant
mechanisms prompting severe manifestations of COVID-19. Objective: To evaluate the …
mechanisms prompting severe manifestations of COVID-19. Objective: To evaluate the …
[HTML][HTML] Type I interferons in COVID-19 pathogenesis
Simple Summary The innate antiviral immune response is essential to limit virus replication
at early stages of infection, thus preventing viral spread and pathogenesis. Nevertheless …
at early stages of infection, thus preventing viral spread and pathogenesis. Nevertheless …
[HTML][HTML] Interleukin-6, CXCL10 and infiltrating macrophages in COVID-19-related cytokine storm: not one for all but all for one!
F Coperchini, L Chiovato, M Rotondi - Frontiers in immunology, 2021 - frontiersin.org
SARS-COV-2 virus is responsible for the ongoing devastating pandemic. Since the early
phase of the pandemic, the “cytokine-storm” appeared a peculiar aspect of SARS-COV-2 …
phase of the pandemic, the “cytokine-storm” appeared a peculiar aspect of SARS-COV-2 …
[HTML][HTML] COVID-19 and the role of cytokines in this disease
A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
[HTML][HTML] Innate immunity, cytokine storm, and inflammatory cell death in COVID-19
R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
The innate immune system serves as the first line of defense against invading pathogens;
however, dysregulated innate immune responses can induce aberrant inflammation that is …
however, dysregulated innate immune responses can induce aberrant inflammation that is …
COVID-19 as an acute inflammatory disease
RH Manjili, M Zarei, M Habibi… - The journal of immunology, 2020 - journals.aai.org
Abstract The 2019 coronavirus disease (COVID-19) pandemic caused by the virus severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created an unprecedented …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created an unprecedented …
[HTML][HTML] Cellular immune response to COVID-19 and potential immune modulators
X Zhou, Q Ye - Frontiers in immunology, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Droplets and contacts serve as …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Droplets and contacts serve as …
Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19
Although most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–infected
individuals experience mild coronavirus disease 2019 (COVID-19), some patients suffer …
individuals experience mild coronavirus disease 2019 (COVID-19), some patients suffer …
Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options
Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global public health
emergency and has led to devastating results. Mounting evidence proposes that the disease …
emergency and has led to devastating results. Mounting evidence proposes that the disease …
An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis
Y Liu, D Chen, J Hou, H Li, D Cao, M Guo, Y Ling… - Cytokine, 2021 - Elsevier
The hyper-inflammatory response is thought to be a major cause of acute respiratory
distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …
distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …