Genesis of a complex disease

J Flint, M Munafo - Nature, 2014 - nature.com
Genesis of a complex disease | Nature Skip to main content Thank you for visiting nature.com.
You are using a browser version with limited support for CSS. To obtain the best experience …

Incriminating genomic evidence

JR Lupski - Nature, 2008 - nature.com
Incriminating genomic evidence | Nature Skip to main content Thank you for visiting nature.com.
You are using a browser version with limited support for CSS. To obtain the best experience …

Genetic origins of schizophrenia find common ground

CO Iyegbe, PF O'Reilly - 2022 - nature.com
Genetic origins of schizophrenia find common ground Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Breaking the gene barrier in schizophrenia

S Horváth, K Mirnics - Nature medicine, 2009 - nature.com
Studies of schizophrenia have been plagued by shortcomings such as weak genetic
association with disease, inadequate animal models and limited replication of gene …

[引用][C] Splitting schizophrenia

ES Lander - Nature, 1988 - nature.com
Splitting schizophrenia Page 1 © 1988 Nature Publishing Group _N_A_T_ll_R_E_V_(_)l_ ..
_.1_.IC_, _111_N_(_JV_E_.M_B_E_"R_llJ_H_K _ _ _ _ _ _ NEWS AND VIEWS------------------I_OS …

From genetics to physiology at last

RS Dhindsa, DB Goldstein - Nature, 2016 - nature.com
From genetics to physiology at last | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Puzzling over schizophrenia: schizophrenia as a pathway disease

PF Sullivan - Nature medicine, 2012 - nature.com
Effective treatment for schizophrenia is still an unmet clinical need. Alleviating problems
associated with cognitive impairment and finding the root of the disease remain priorities for …

A polygenic burden of rare disruptive mutations in schizophrenia

SM Purcell, JL Moran, M Fromer, D Ruderfer… - Nature, 2014 - nature.com
Schizophrenia is a common disease with a complex aetiology, probably involving multiple
and heterogeneous genetic factors. Here, by analysing the exome sequences of 2,536 …

Common variants conferring risk of schizophrenia

H Stefansson, RA Ophoff, S Steinberg, OA Andreassen… - Nature, 2009 - nature.com
Schizophrenia is a complex disorder, caused by both genetic and environmental factors and
their interactions. Research on pathogenesis has traditionally focused on neurotransmitter …

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

… Consortium Manuscript preparation Purcell Shaun M … - Nature, 2009 - nature.com
Schizophrenia is a severe mental disorder with a lifetime risk of about 1%, characterized by
hallucinations, delusions and cognitive deficits, with heritability estimated at up to 80%,. We …