Contribution of Pseudomonas aeruginosa Exopolysaccharides Pel and Psl to Wound Infections

D Fleming, B Niese, W Redman… - Frontiers in Cellular …, 2022 - frontiersin.org
Biofilms are the cause of most chronic bacterial infections. Living within the biofilm matrix,
which is made of extracellular substances, including polysaccharides, proteins, eDNA, lipids …

Regulation of Biofilm Exopolysaccharide Biosynthesis and Degradation in Pseudomonas aeruginosa

LZ Ma, D Wang, Y Liu, Z Zhang… - Annual review of …, 2022 - annualreviews.org
Microbial communities enmeshed in a matrix of macromolecules, termed as biofilms, are the
natural setting of bacteria. Exopolysaccharide is a critical matrix component of biofilms …

Dynamic remodeling of microbial biofilms by functionally distinct exopolysaccharides

SC Chew, B Kundukad, T Seviour, JRC Van der Maarel… - MBio, 2014 - Am Soc Microbiol
Biofilms are densely populated communities of microbial cells protected and held together
by a matrix of extracellular polymeric substances. The structure and rheological properties of …

The Pel Polysaccharide Can Serve a Structural and Protective Role in the Biofilm Matrix of Pseudomonas aeruginosa

KM Colvin, VD Gordon, K Murakami, BR Borlee… - PLoS …, 2011 - journals.plos.org
Bacterial extracellular polysaccharides are a key constituent of the extracellular matrix
material of biofilms. Pseudomonas aeruginosa is a model organism for biofilm studies and …

Beyond the Wall: Exopolysaccharides in the Biofilm Lifestyle of Pathogenic and Beneficial Plant-Associated Pseudomonas

Z Heredia-Ponce, A de Vicente, FM Cazorla… - Microorganisms, 2021 - mdpi.com
The formation of biofilms results from a multicellular mode of growth, in which bacteria
remain enwrapped by an extracellular matrix of their own production. Many different bacteria …

Role of exopolysaccharides in Pseudomonas aeruginosa biofilm formation and architecture

A Ghafoor, ID Hay, BHA Rehm - Applied and environmental …, 2011 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic human pathogen and has been established
as a model organism to study bacterial biofilm formation. At least three exopolysaccharides …

Assembly and Development of the Pseudomonas aeruginosa Biofilm Matrix

L Ma, M Conover, H Lu, MR Parsek, K Bayles… - PLoS …, 2009 - journals.plos.org
Virtually all cells living in multicellular structures such as tissues and organs are encased in
an extracellular matrix. One of the most important features of a biofilm is the extracellular …

Pseudomonas aeruginosa PAO1 exopolysaccharides are important for mixed species biofilm community development and stress tolerance

S Periasamy, HAS Nair, KWK Lee, J Ong… - Frontiers in …, 2015 - frontiersin.org
Pseudomonas aeruginosa PAO1 produces three polysaccharides, alginate, Psl, and Pel that
play distinct roles in attachment and biofilm formation for monospecies biofilms …

The extracellular polysaccharide matrix of Pseudomonas aeruginosa biofilms is a determinant of polymorphonuclear leukocyte responses

M Rybtke, PØ Jensen, CH Nielsen… - Infection and …, 2020 - Am Soc Microbiol
Bacterial biofilms may cause chronic infections due to their ability to evade clearance by the
immune system and antibiotics. The persistent biofilms induce a hyperinflammatory state …

Role of Pseudomonas aeruginosa lipopolysaccharides in modulation of biofilm and virulence factors of Enterobacteriaceae

SH Abdel-Rhman - Annals of Microbiology, 2019 - Springer
Enterobacteriaceae members are largely distributed in the environment and responsible for
a wide range of bacterial infections in hospitalized patients. Pseudomonas aeruginosa (P …