CRISPR-Cas system, antibiotic resistance and virulence in bacteria: through a common lens

S Roy, S Naha, A Rao, S Basu - Progress in Molecular Biology and …, 2021 - Elsevier
CRISPR-Cas system, antibiotic resistance and virulence are different modes of survival for
the bacteria. CRISPR-Cas is an adaptive immune system that can degrade foreign DNA …

[HTML][HTML] Anti-CRISPR proteins as a therapeutic agent against drug-resistant bacteria

P Vyas - Microbiological research, 2022 - Elsevier
The continuous deployment of various antibiotics to treat multiple serious bacterial infections
leads to multidrug resistance among the bacterial population. It has failed the standard …

Harnessing the CRISPR-Cas systems to combat antimicrobial resistance

C Duan, H Cao, LH Zhang, Z Xu - Frontiers in Microbiology, 2021 - frontiersin.org
The emergence of antimicrobial-resistant (AMR) bacteria has become one of the most
serious threats to global health, necessitating the development of novel antimicrobial …

The application of the CRISPR-Cas system in antibiotic resistance

S Tao, H Chen, N Li, W Liang - Infection and drug resistance, 2022 - Taylor & Francis
The emergence and global epidemic of antimicrobial resistance (AMR) poses a serious
threat to global public health in recent years. AMR genes are shared between bacterial …

CRISPR-Cas system in regulation of immunity and virulence of bacterial pathogens

W Ahmed, MA Hafeez, R Ahmad, S Mahmood - Gene Reports, 2018 - Elsevier
Microbes rely on multiple immune defense mechanisms that permit them to withstand viral
predation and exposure to invading nucleic acid. In prokaryotes, clustered regularly …

CRISPR-Cas system as a promising player against bacterial infection and antibiotic resistance

M Abavisani, R Khayami, M Hoseinzadeh… - Drug Resistance …, 2023 - Elsevier
The phenomenon of antibiotic resistance (AR) and its increasing global trends and
destructive waves concerns patients and the healthcare system. In order to combat AR, it is …

The CRISPR-Cas app goes viral

ML Lemay, P Horvath, S Moineau - Current opinion in microbiology, 2017 - Elsevier
Highlights•CRISPR spacer content is a gold mine of information to learn about the past
genetic environments of microbial populations.•Bacteria of industrial interest can be …

[HTML][HTML] CRISPR–Cas: complex functional networks and multiple roles beyond adaptive immunity

G Faure, KS Makarova, EV Koonin - Journal of molecular biology, 2019 - Elsevier
CRISPR–Cas is a prokaryotic adaptive immune system that functions by incorporating
fragments of foreign DNA into CRISPR arrays. The arrays containing spacers derived from …

CRISPR patent results

S Starling - Nature Reviews Microbiology, 2017 - nature.com
CRISPR patent results | Nature Reviews Microbiology Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Molecular mechanisms of CRISPR-mediated microbial immunity

G Gasiunas, T Sinkunas, V Siksnys - Cellular and molecular life sciences, 2014 - Springer
Bacteriophages (phages) infect bacteria in order to replicate and burst out of the host, killing
the cell, when reproduction is completed. Thus, from a bacterial perspective, phages pose a …