The coupling of liquid chromatography to mass spectrometry (LC-MS) has been the subject of intense research since the pioneering work of Tal'roze et aZ. 1 over 20 years ago. On-line …
TA Bellar, TD Behymer, WL Budde - Journal of the American …, 1990 - ACS Publications
Enhancements in ion abundances in high-performance liquid chromatography (HPLC) particle beam (PB) mass spectrometry were observed during coelution or when certain …
In pharmaceutical analysis, ie the analytical development and quality control of drug substances and dosage forms, mass spectrometry (MS) combined with chromatographic …
The combination of HPLC and mass spectrometry has great promise for the toxicology laboratory. In the past five years, significant progress has been made toward producing a …
RS Plumb, GJ Dear, DN Mallett, DM Higton… - Xenobiotica, 2001 - Taylor & Francis
1. The development of bio-analysis of drug molecules over the last 10 years is reviewed, focusing on advances in sample preparation, liquid chromatography and detection. 2 …
A novel paper spray cartridge with an integrated solid phase extraction (SPE) column is described. The cartridge performs extraction and pre-concentration, as well as sample …
G Balizs, A Hewitt - Analytica Chimica Acta, 2003 - Elsevier
This paper describes the principles, the current technology and the applications of HPLC and tandem mass spectrometry (LC–MS–MS) in the analysis of veterinary drug residues …
Y Liu, Z Lin, S Zhang, C Yang, X Zhang - Analytical and bioanalytical …, 2009 - Springer
A high-throughput method for rapid screening of active ingredients in drugs has been developed with mass spectrometry coupled to a low-temperature plasma (LTP) probe ion …
CR Mallet, JR Mazzeo, U Neue - Rapid Communications in …, 2001 - Wiley Online Library
Abstract Several configurations using 6‐and 10‐port switching valves were studied for high flow, on‐line extraction of rat plasma coupled to an electrospray triple quadrupole mass …