Simulating the hallmarks of cancer
Cancer can be viewed as the loss of cooperative cell behaviors that normally facilitate
multicellularity, including the formation of tissues and organs. Hanahan and Weinberg …
multicellularity, including the formation of tissues and organs. Hanahan and Weinberg …
Decision support systems in oncology
S Walsh, EEC de Jong, JE van Timmeren… - JCO clinical cancer …, 2019 - ascopubs.org
Precision medicine is the future of health care: please watch the animation at https://vimeo.
com/241154708. As a technology-intensive and-dependent medical discipline, oncology will …
com/241154708. As a technology-intensive and-dependent medical discipline, oncology will …
An integrated network-based mechanistic model for tumor growth dynamics under drug administration
D Ribeiro, JM Pinto - Computers in biology and medicine, 2009 - Elsevier
Cancer chemotherapy complexity ranges from the routes that the drug must follow before
reaching the tumor site (pharmacokinetics), to the drug effects on tumor depletion …
reaching the tumor site (pharmacokinetics), to the drug effects on tumor depletion …
Quantitative in vivo imaging to enable tumour forecasting and treatment optimization
Current clinical decision-making in oncology relies on averages of large patient populations
to both assess tumour status and treatment outcomes. However, cancers exhibit an inherent …
to both assess tumour status and treatment outcomes. However, cancers exhibit an inherent …
[HTML][HTML] Towards predicting the response of a solid tumour to chemotherapy and radiotherapy treatments: clinical insights from a computational model
GG Powathil, DJA Adamson… - PLoS computational …, 2013 - journals.plos.org
In this paper we use a hybrid multiscale mathematical model that incorporates both
individual cell behaviour through the cell-cycle and the effects of the changing …
individual cell behaviour through the cell-cycle and the effects of the changing …
Multiscale tumor modeling with drug pharmacokinetic and pharmacodynamic profile using stochastic hybrid system
Effective cancer treatment strategy requires an understanding of cancer behavior and
development across multiple temporal and spatial scales. This has resulted into a growing …
development across multiple temporal and spatial scales. This has resulted into a growing …
Chemo‐mechanistic multi‐scale model of a three‐dimensional tumor microenvironment to quantify the chemotherapy response of cancer
MR Nikmaneshi, B Firoozabadi… - Biotechnology and …, 2021 - Wiley Online Library
Exploring efficient chemotherapy would benefit from a deeper understanding of the tumor
microenvironment (TME) and its role in tumor progression. As in vivo experimental methods …
microenvironment (TME) and its role in tumor progression. As in vivo experimental methods …
[图书][B] New challenges for cancer systems biomedicine
A D'Onofrio, P Cerrai, A Gandolfi - 2012 - Springer
The future of oncology has a name: Molecular Medicine (MM). Molecular Medicine is a new
science based on three pillars. Two of them are well known and evident in its very name …
science based on three pillars. Two of them are well known and evident in its very name …
[HTML][HTML] Cancer models
M Breitenbach, J Hoffmann - Frontiers in oncology, 2018 - frontiersin.org
Cancer is still a major concern for public health and is a cause of death while being
psychologically the most dreaded disease. Until recent times, the diagnosis of a progressed …
psychologically the most dreaded disease. Until recent times, the diagnosis of a progressed …
A multi-scale agent-based model for avascular tumour growth
In this paper, we have developed a multi-scale, lattice-free, agent based model of avascular
tumour growth in epithelial tissue. The model integrates different events to identify the …
tumour growth in epithelial tissue. The model integrates different events to identify the …