Genetically predicted testosterone and cardiovascular risk factors in men: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study

J Zhao, C Jiang, TH Lam, B Liu… - International journal …, 2014 - academic.oup.com
Background Observationally lower testosterone is associated with an unhealthier
cardiovascular (CVD) risk profile, but this association is open to confounding and reverse …

Genetic determinants of serum testosterone concentrations in men

C Ohlsson, H Wallaschofski, KL Lunetta, L Stolk… - PLoS …, 2011 - journals.plos.org
Testosterone concentrations in men are associated with cardiovascular morbidity,
osteoporosis, and mortality and are affected by age, smoking, and obesity. Because of …

[HTML][HTML] Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: a Mendelian randomization investigation

CM Schooling, S Luo, SLA Yeung… - International journal of …, 2018 - Elsevier
Background Testosterone supplementation has been linked to increased cardiovascular
disease risk in some observational studies. The causal role of testosterone can be …

Endogenous testosterone and cardiovascular disease in healthy men: a meta-analysis

JB Ruige, AM Mahmoud, D De Bacquer, JM Kaufman - Heart, 2011 - heart.bmj.com
Context The literature provides no clear answer as to whether low endogenous testosterone
increases risk of cardiovascular disease (CVD) in healthy men. Objective Our purpose was …

Low testosterone concentrations in men contribute to the gender gap in cardiovascular morbidity and mortality

R Haring, U John, H Völzke, M Nauck, M Dörr, SB Felix… - Gender medicine, 2012 - Elsevier
BACKGROUND: Across the industrialized world, men experience an earlier onset of
cardiovascular disease (CVD) and a life expectancy 5 to 10 years shorter than women. Low …

Mendelian randomization suggests non‐causal associations of testosterone with cardiometabolic risk factors and mortality

R Haring, A Teumer, U Völker, M Dörr, M Nauck… - …, 2013 - Wiley Online Library
Prospective studies showed that low serum testosterone concentrations are associated with
various cardiometabolic risk factors and mortality. However, the causal nature of these …

Endogenous testosterone and its relationship to preclinical and clinical measures of cardiovascular disease in the atherosclerosis risk in communities study

R Srinath, S Hill Golden, KA Carson… - The Journal of Clinical …, 2015 - academic.oup.com
Context: Epidemiologic studies suggest that endogenous testosterone (T) levels in males
may be implicated in cardiovascular disease (CVD), however further clarification is needed …

New evidence for the effect of type 2 diabetes and glycemic traits on testosterone levels: a two-sample Mendelian randomization study

C Jiang, Y Wang, W Yang, X Yang - Frontiers in Endocrinology, 2023 - frontiersin.org
Objective Type 2 diabetes mellitus (T2DM) is an endocrine-related disease with an
increasing incidence worldwide. Male sexual dysfunction is common in diabetic patients …

[HTML][HTML] Analysis of cardiovascular risk factors associated with serum testosterone levels according to the US 2011–2012 National Health and Nutrition Examination …

C Deng, Z Zhang, H Li, P Bai, X Cao, AS Dobs - The Aging Male, 2019 - Taylor & Francis
Objective: To investigate associations between cardiovascular disease risk factors, including
fasting glucose, cholesterol, high density lipoprotein cholesterol (HDL-c), LDL-c, blood …

Endogenous testosterone levels and cardiovascular risk: meta-analysis of observational studies

G Corona, G Rastrelli, G Di Pasquale… - The journal of sexual …, 2018 - academic.oup.com
Introduction The relationship between endogenous testosterone (T) levels and
cardiovascular (CV) risk in men is conflicting. Aim To verify whether endogenous T levels …