The expression level of angiotensin-converting enzyme 2 determines the severity of COVID-19: lung and heart tissue as targets

MMN Babadaei, A Hasan, SH Bloukh… - Journal of …, 2021 - Taylor & Francis
Researchers have reported some useful information about the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) leading to CoV disease 2019 (COVID-19). Several …

A computational and bioinformatic analysis of ACE2: an elucidation of its dual role in COVID-19 pathology and finding its associated partners as potential therapeutic …

ATA Khan, Z Khalid, H Zahid, MA Yousaf… - Journal of …, 2022 - Taylor & Francis
Despite the continued global spread of the current COVID-19 pandemic, the nonavailability
of a vaccine or targeted drug against this disease is still prevailing. The most established …

Effects of SARS-CoV-2 on cardiovascular system: the dual role of angiotensin-converting enzyme 2 (ACE2) as the virus receptor and homeostasis regulator-review

A Aleksova, G Gagno, G Sinagra, AP Beltrami… - International journal of …, 2021 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2) is the entry receptor for severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), the cause of Coronavirus Disease-2019 (COVID …

Coronavirus disease 2019 (COVID-19): Biophysical and biochemical aspects of SARS-CoV-2 and general characteristics

G Güler, H Özdemir, D Omar, G Akdoğan - Progress in Biophysics and …, 2021 - Elsevier
Abstract The coronavirus disease (COVID-19) arises from the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) which is an enveloped RNA virus. COVID-19 has …

ACE2 is an adjacent element of atherosclerosis and COVID-19 pathogenesis

AV Poznyak, EE Bezsonov, AH Eid… - International Journal of …, 2021 - mdpi.com
COVID-19 is a highly contagious new infection caused by the single-stranded RNA Sars-
CoV-2 virus. For the first time, this infection was recorded in December 2019 in the Chinese …

Review on COVID-19 etiopathogenesis, clinical presentation and treatment available with emphasis on ACE2

H Rathi, V Burman, SK Datta, SV Rana… - Indian Journal of Clinical …, 2021 - Springer
Abstract In December 2019, Wuhan city in the Hubei province of China reported for the first
time a cluster of patients infected with a novel coronavirus, since then there has been an …

Molecular pathogenesis, immunopathogenesis and novel therapeutic strategy against COVID-19

SK Chatterjee, S Saha, MNM Munoz - Frontiers in molecular …, 2020 - frontiersin.org
The coronavirus disease 2019 (COVID-19), is a highly contagious transmittable disease
caused by a recently discovered coronavirus, pathogenic SARS-CoV-2. Followed by the …

[HTML][HTML] A comprehensive investigation of the mRNA and protein level of ACE2, the putative receptor of SARS-CoV-2, in human tissues and blood cells

Y Wang, Y Wang, W Luo, L Huang, J Xiao… - … journal of medical …, 2020 - ncbi.nlm.nih.gov
The outbreak of pneumonia caused by SARS-CoV-2 posed a great threat to global human
health, which urgently requires us to understand comprehensively the mechanism of SARS …

The role of SARS‐CoV‐2 target ACE2 in cardiovascular diseases

H Zhu, L Zhang, Y Ma, M Zhai, L Xia… - Journal of Cellular …, 2021 - Wiley Online Library
Abstract SARS‐CoV‐2, the virus responsible for the global coronavirus disease (COVID‐19)
pandemic, attacks multiple organs of the human body by binding to angiotensin‐converting …

Determining available strategies for prevention and therapy: Exploring COVID‑19 from the perspective of ACE2

L Cai, X Guo, Y Cao, P Ying… - International …, 2021 - spandidos-publications.com
Abstract Coronavirus disease 2019 (COVID‑19) is an acute infectious pneumonia caused by
a novel type of coronavirus infection. There are currently no clinically available specific …