Continuous reactive oxygen species (ROS) production in individuals with sickle cell disease
(SCD) may alter their overall redox status and cause tissue damage. The aim of this study …

Background: Sickle cell anemia (SCA) is an inherited blood disease with known
complications as a result of certain pathophysiological dysfunctions. It has been suggested …

Background: Sickle cell disease (SCD) is a hereditary hemoglobinopathy characterized by
hemolytic anemia. The oxidative phenomena play a significant role in its pathophysiology …

Sickle cell anemia (SCA) is a hereditary disorder with higher potential for oxidative damage
due to chronic redox imbalance in red cells. We measured antioxidant enzymes including …

Background Sickle cell disease (SCD) is a class of hemoglobinopathy resulting from a
single mutation in the ß-globin chain inducing the substitution of valine for glutamic acid at …

Oxidative stress plays a very significant role in the pathophysiology of sickle cell disease
(SCD) and associated complications. Oxidative stress, which is often experienced by SCD …

Objectives: This study was conducted to assess the markers of oxidative stress,
myeloperoxidase (MPO), acetylcholinesterase (AChE) and xanthine oxidase (XO) activities …

Congenital hemoglobin mutations may alter the delicate balance of free-radical generation
and antioxidant defense systems in the red cell. Oxidative stress may thus play a role in the …

Background: The phenotypic expression of sickle cell disease (SCD) is a complex
pathophysiologic condition. However, sickle erythrocytes might be the cause for multiple …

Sickle cell disease (SCD) is a hemoglobinopathy characterized by hemolytic anemia,
increased susceptibility to infections and vaso‐occlusion leading to a reduced quality of life …