Methods for exploring the faecal microbiome of premature infants: a review

JAF Westaway, R Huerlimann, CM Miller… - … health, neonatology and …, 2021 - Springer
The premature infant gut microbiome plays an important part in infant health and
development, and recognition of the implications of microbial dysbiosis in premature infants …

Factors associated with the microbiome in moderate–late preterm babies: a cohort study from the DIAMOND randomized controlled trial

CYL Chong, T Vatanen, T Alexander… - Frontiers in cellular …, 2021 - frontiersin.org
The gut microbiota of preterm infants is affected by perinatal factors and, in turn, may impact
upon infant health. In this study, we collected fecal samples at Day-10 (D10) and 4-months …

[HTML][HTML] A protocol for characterization of extremely preterm infant gut microbiota in double-blind clinical trials

M Martí, JE Spreckels, MC Jenmalm, T Abrahamsson - STAR protocols, 2021 - Elsevier
Summary 16S rRNA gene sequencing enables microbial community profiling, but
recovering fecal DNA from extremely premature infants is challenging. Here, we describe an …

Optimisation of 16S rRNA gut microbiota profiling of extremely low birth weight infants

C Alcon-Giner, S Caim, S Mitra, J Ketskemety… - BMC genomics, 2017 - Springer
Background Infants born prematurely, particularly extremely low birth weight infants (ELBW)
have altered gut microbial communities. Factors such as maternal health, gut immaturity …

The premature infant gut microbiome during the first 6 weeks of life differs based on gestational maturity at birth

DA Chernikova, JC Madan, ML Housman… - Pediatric …, 2018 - nature.com
Background The impact of degree of prematurity at birth on premature infant gut microbiota
has not been extensively studied in comparison to term infants in large cohorts. Methods To …

Dichotomous development of the gut microbiome in preterm infants

TTB Ho, MW Groer, B Kane, AL Yee, BA Torres… - Microbiome, 2018 - Springer
Background Preterm infants are at risk of developing intestinal dysbiosis with an increased
proportion of Gammaproteobacteria. In this study, we sought the clinical determinants of the …

The development of gut microbiota in critically ill extremely low birth weight infants assessed with 16S rRNA gene based sequencing

T Drell, I Lutsar, J Štšepetova, Ü Parm, T Metsvaht… - Gut …, 2014 - Taylor & Francis
Objective: An increasing number of studies that are using high-throughput molecular
methods are rapidly extending our knowledge of gut microbial colonization in preterm …

Cesarean or vaginal birth does not impact the longitudinal development of the gut microbiome in a cohort of exclusively preterm infants

CJ Stewart, ND Embleton, E Clements… - Frontiers in …, 2017 - frontiersin.org
The short and long-term impact of birth mode on the developing gut microbiome in neonates
has potential implications for the health of infants. In term infants, the microbiome …

[HTML][HTML] Differences in the bacterial profiles of infant gut by birth process, milk diet, and choice of 16S rRNA gene target region

MA Biol-Aquino, CJ Perdiz, M Borlagdan… - Human Microbiome …, 2019 - Elsevier
Perinatal factors such as birth process and milk diet have been known to greatly influence
the development of gut microbiota, which is often studied using amplicon sequencing of the …

The individual-specific and diverse nature of the preterm infant microbiota

E Barrett, C Kerr, K Murphy, O O'Sullivan… - Archives of Disease in …, 2013 - fn.bmj.com
Objective To examine the composition of the evolving microbiota of preterm infants at weeks
2 and 4 of life. Settings The paediatric intensive care unit of the Cork University Maternity …