Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?

LYR Wong, S Perlman - Nature Reviews Immunology, 2022 - nature.com
Human coronaviruses cause a wide spectrum of disease, ranging from mild common colds
to acute respiratory distress syndrome and death. Three highly pathogenic human …

Unraveling the mystery surrounding post-acute sequelae of COVID-19

RK Ramakrishnan, T Kashour, Q Hamid… - Frontiers in …, 2021 - frontiersin.org
More than one year since its emergence, corona virus disease 2019 (COVID-19) is still
looming large with a paucity of treatment options. To add to this burden, a sizeable subset of …

[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–current perspectives

JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …

[HTML][HTML] Immune response, inflammation, and the clinical spectrum of COVID-19

LF García - Frontiers in immunology, 2020 - frontiersin.org
The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly
extended to become a global sanitary and economic emergency. Its etiological agent is the …

[HTML][HTML] Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review

A Shafqat, S Shafqat, SA Salameh, J Kashir… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …

Immune mechanisms underlying COVID-19 pathology and post-acute sequelae of SARS-CoV-2 infection (PASC)

S Mohandas, P Jagannathan, TJ Henrich, ZA Sherif… - Elife, 2023 - elifesciences.org
With a global tally of more than 500 million cases of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections to date, there are growing concerns about the post …

[HTML][HTML] The immune response and immunopathology of COVID-19

E Mortaz, P Tabarsi, M Varahram, G Folkerts… - Frontiers in …, 2020 - frontiersin.org
Coronaviruses were first discovered in the 1960s and are named due to their crown-like
shape. Sometimes, but not often, a coronavirus can infect both animals and humans. An …

The immunology and immunopathology of COVID-19

M Merad, CA Blish, F Sallusto, A Iwasaki - Science, 2022 - science.org
Considerable research effort has been made worldwide to decipher the immune response
triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …

[HTML][HTML] Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

C Phetsouphanh, DR Darley, DB Wilson, A Howe… - Nature …, 2022 - nature.com
A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection
develop post-acute COVID syndrome (long COVID (LC)) lasting longer than 12 weeks. Here …

The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …