Differentiation antagonizing non‐protein coding RNA knockdown alleviates lipopolysaccharide‐induced inflammatory injury and apoptosis in human chondrocyte …

X Li, X Wei, S Wang, G Sun, Y Zhao, H Yin… - Orthopaedic …, 2021 - Wiley Online Library
Objective To confirm the role of long noncoding RNA differentiation antagonizing non‐
protein coding RNA (DANCR) in chondrocyte inflammatory injury in osteoarthritis (OA) in …

lncRNA‑NR024118 overexpression reverses LPS‑induced inflammatory injury and apoptosis via NF‑κB/Nrf2 signaling in ATDC5 chondrocytes

X Mei, J Tong, W Zhu, Y Zhu - Molecular Medicine …, 2019 - spandidos-publications.com
Osteoarthritis (OA) is one of the most prevalent types of chronic joint diseases. Chondrocytes
survival is closely associated with the destruction of joints in patients with OA. Long …

Overexpression of lncRNA LINC00665 inhibits the proliferation and chondroblast differentiation of bone marrow mesenchymal stem cells by targeting miR-214-3p

S Chen, H Liu, Y Wang, S Wang, B Yang, D Sun… - Journal of Orthopaedic …, 2024 - Springer
Background Osteoarthritis is a chronic disease mainly involving the damage of articular
cartilage and the whole articular tissue, which is the main cause of disability in the elderly …

[HTML][HTML] miR‑146a‑5p expression is upregulated by the CXCR4 antagonist TN14003 and attenuates SDF‑1‑induced cartilage degradation

D Jia, Y Li, R Han, K Wang, G Cai… - Molecular …, 2019 - spandidos-publications.com
Osteoarthritis (OA) is an aseptic inflammatory disease which is associated with the stromal
cell‑derived factor 1/C‑X‑C chemokine receptor type 4 (SDF‑1/CXCR4) axis. Accumulating …

Identify CRNDE and LINC00152 as the key lncRNAs in age-related degeneration of articular cartilage through comprehensive and integrative analysis

P Hu, F Sun, J Ran, L Wu - PeerJ, 2019 - peerj.com
Background Osteoarthritis (OA) is one of the most important age-related degenerative
diseases, and the leading cause of disability and chronic pain in the aging population …

LncRNA HAGLR silencing inhibits IL-1β-induced chondrocytes inflammatory injury via miR-130a-3p/JAK1 axis

Y Zuo, C Xiong, X Gan, W Xie, X Yan, Y Chen… - Journal of Orthopaedic …, 2023 - Springer
Background Osteoarthritis (OA), the most common form of arthritis, is accompanied by
destruction of articular cartilage, development of osteophyte and sclerosis of subchondral …

miR-181a-5p targets DDX3X to inhibit the progression of osteoarthritis via NF-ΚB signaling pathway

P Zhao, G Ma, L Ma - Journal of Orthopaedic Surgery and Research, 2023 - Springer
Osteoarthritis (OA) is the most common age-related joint disease, characterized by chronic
inflammation, progressive articular cartilage destruction and subchondral osteosclerosis …

Systematic analysis of transcriptomic profile of chondrocytes in osteoarthritic knee using next-generation sequencing and bioinformatics

YJ Chen, WA Chang, LY Wu, YL Hsu, CH Chen… - Journal of Clinical …, 2018 - mdpi.com
The phenotypic change of chondrocytes and the interplay between cartilage and
subchondral bone in osteoarthritis (OA) has received much attention. Structural changes …

Expression profiles of long non‑coding RNAs in the cartilage of patients with knee osteoarthritis and normal individuals

Y Liu, J Jing, H Yu, J Zhang, Q Cao… - Experimental and …, 2021 - spandidos-publications.com
Knee osteoarthritis is caused by a multifactorial imbalance in the synthesis and degradation
of knee chondrocytes, subchondral bone and extracellular matrix. Abnormal expression of …

Long non-protein coding RNA DANCR functions as a competing endogenous RNA to regulate osteoarthritis progression via miR-577/SphK2 axis

X Fan, J Yuan, J Xie, Z Pan, X Yao, X Sun… - Biochemical and …, 2018 - Elsevier
Long noncoding RNAs (lncRNAs) have been known to be involved in multiple diverse
diseases, including osteoarthritis (OA). This study aimed to explore the role of differentiation …