Comparative pathology of the nasal epithelium in K18-hACE2 Tg mice, hACE2 Tg mice, and hamsters infected with SARS-CoV-2

P Yu, W Deng, L Bao, Y Qu, Y Xu, W Zhao… - Veterinary …, 2022 - journals.sagepub.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes severe viral
pneumonia and is associated with a high fatality rate. A substantial proportion of patients …

Effects of COVID-19 on the human central olfactory system: A natural pre-post experiment

E Thunell, MG Peter, V Lenoir… - American Journal …, 2022 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Reduced olfactory function is the symptom with the
highest prevalence in coronavirus disease 2019 (COVID-19) with nearly 70% of infected …

SARS-CoV-2 receptors and entry genes are expressed in the human olfactory neuroepithelium and brain

L Fodoulian, J Tuberosa, D Rossier, M Boillat, C Kan… - Iscience, 2020 - cell.com
Reports indicate an association between COVID-19 and anosmia, as well as the presence
of SARS-CoV-2 virions in the olfactory bulb. To test whether the olfactory neuroepithelium …

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

J Meinhardt, J Radke, C Dittmayer, J Franz… - Nature …, 2021 - nature.com
The newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
causes COVID-19, a pandemic respiratory disease. Moreover, thromboembolic events …

Olfactory dysfunction as a post-infectious symptom of SARS-CoV-2 infection

BA Othman, SQ Maulud, PJ Jalal… - Annals of Medicine …, 2022 - journals.lww.com
The unexpected onset smell and taste disability was being recognized as a COVID-19
related symptom. Loss of smell might occur alone or be followed by other COVID-19 …

[HTML][HTML] Neuroinvasion and encephalitis following intranasal inoculation of SARS-CoV-2 in K18-hACE2 mice

P Kumari, HA Rothan, JP Natekar, S Stone, H Pathak… - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can cause
neurological disease in humans, but little is known about the pathogenesis of SARS-CoV-2 …

Anosmia: a missing link in the neuroimmunology of coronavirus disease 2019 (COVID-19)

N Yazdanpanah, A Saghazadeh… - Reviews in the …, 2020 - degruyter.com
Just before 2020 began, a novel coronavirus, severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), brought for humans a potentially fatal disease known as …

Persistent post–COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium

JB Finlay, DH Brann, R Abi Hachem, DW Jang… - Science translational …, 2022 - science.org
SARS-CoV-2 causes profound changes in the sense of smell, including total smell loss.
Although these alterations are often transient, many patients with COVID-19 exhibit olfactory …

[PDF][PDF] The effect of coronaviruses on olfaction: systematic review

M Zugaj, NS van Ditzhuijzen, K Golebski, WJ Fokkens - Rhinology, 2021 - researchgate.net
Background: Unlike other respiratory viruses, SARS-CoV-2 causes anosmia without
sinonasal inflammation. Here we systematically review the effects of the 7 known human …

Reduced T-cell densities in cranial nerves of patients who died with SARS-CoV-2 infection

J Bremer, J Friemann, S von Stillfried, P Boor… - Acta Neuropathologica …, 2023 - Springer
SARS-CoV-2 patients show a highly variable disease course, ranging from asymptomatic
infections to critical illness and death. Most of the fatalities occur in the older patient …