MoS2-Plasmonic Nanocavities for Raman Spectra of Single Extracellular Vesicles Reveal Molecular Progression in Glioblastoma

M Jalali, C del Real Mata, L Montermini, O Jeanne… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are continually released from cancer cells into biofluids, carrying
actionable molecular fingerprints of the underlying disease with considerable diagnostic and …

Plasmonic nanobowtiefluidic device for sensitive detection of glioma extracellular vesicles by Raman spectrometry

M Jalali, II Hosseini, T AbdelFatah, L Montermini… - Lab on a Chip, 2021 - pubs.rsc.org
Cancer cells shed into biofluids extracellular vesicles (EVs)—nanoscale membrane particles
carrying diagnostic information. EVs shed by heterogeneous populations of tumor cells offer …

Enabling sensitive phenotypic profiling of cancer-derived small extracellular vesicles using surface-enhanced Raman spectroscopy nanotags

W Zhang, L Jiang, RJ Diefenbach, DH Campbell… - ACS …, 2020 - ACS Publications
Circulating cancer-derived small extracellular vesicles (EVs) are nanoscale membranous
vesicles shed from cancer cells that are released into surrounding body fluids. Small EVs …

Emerging integrated SERS-microfluidic devices for analysis of cancer-derived small extracellular vesicles

L Ngo, A Tukova, A Hassanzadeh-Barforoushi… - Lab on a Chip, 2023 - pubs.rsc.org
Cancer-derived small extracellular vesicles (sEVs) are specific subgroups of lipid bilayer
vesicles secreted from cancer cells to the extracellular environment. They carry distinct …

Single particle automated Raman trapping analysis of breast cancer cell-derived extracellular vesicles as cancer biomarkers

J Penders, A Nagelkerke, EM Cunnane, SV Pedersen… - ACS …, 2021 - ACS Publications
Extracellular vesicles (EVs) secreted by cancer cells provide an important insight into cancer
biology and could be leveraged to enhance diagnostics and disease monitoring. This paper …

Hybrid nanoplasmonic porous biomaterial scaffold for liquid biopsy diagnostics using extracellular vesicles

T Rojalin, HJ Koster, J Liu, RR Mizenko, D Tran… - ACS …, 2020 - ACS Publications
For more effective early-stage cancer diagnostics, there is a need to develop sensitive and
specific, non-or minimally invasive, and cost-effective methods for identifying circulating …

A Magnetically Driven Tandem Chip Enables Rapid Isolation and Multiplexed Profiling of Extracellular Vesicles

G Zhang, Y Wang, W Zhou, Y Lei, J Lu… - Angewandte …, 2023 - Wiley Online Library
The protein phenotypes of extracellular vesicles (EVs) have emerged as promising
biomarkers for cancer diagnosis and treatment monitoring. However, the technical …

Improved label-free identification of individual exosome-like vesicles with Au@ Ag nanoparticles as SERS substrate

JC Fraire, S Stremersch, D Bouckaert… - … applied materials & …, 2019 - ACS Publications
Exosome-like vesicles (ELVs) are nanovectors released by cells that are endowed with a
variety of molecules, including proteins, nucleic acids, and chemicals that reflect the …

An integrated microfluidic‐SERS platform enables sensitive phenotyping of serum extracellular vesicles in early stage melanomas

J Wang, YC Kao, Q Zhou, A Wuethrich… - Advanced Functional …, 2022 - Wiley Online Library
Precise detection of early melanomas is essential as the stage of disease guides treatment
options. One growing field that may facilitate the advancement of early melanoma detection …

Immuno-capture of extracellular vesicles for individual multi-modal characterization using AFM, SEM and Raman spectroscopy

P Beekman, A Enciso-Martinez, HS Rho, SP Pujari… - Lab on a Chip, 2019 - pubs.rsc.org
Tumor-derived extracellular vesicles (tdEVs) are promising blood biomarkers for cancer
disease management. However, blood is a highly complex fluid that contains multiple …