Exaggerated oxidative stress and hyper-inflammation are essential features of
oxidative/inflammatory diseases. Simultaneously, both processes may be the cause or …

Energy intake and metabolic balance are the pillars of health preservation. Overnutrition
causes nonspecific, persistently low inflammatory state known as metabolic inflammation …

Although two main hypotheses of mitochondrial origin have been proposed, ie, the
autogenous and the endosymbiotic, only the second is being seriously considered currently …

Significance: The growing importance of mitochondria in the immune response and
inflammation is multifaceted. Unraveling the different mechanisms by which mitochondria …

Inflammation is associated with the release of soluble mediators that drive cellular activation
and migration of inflammatory leukocytes to the site of injury, together with endothelial …

A decline in mitochondrial redox homeostasis has been associated with the development of
a wide range of inflammatory-related diseases. Continue discoveries demonstrate that …

Mitochondria are organelles with highly dynamic ultrastructure maintained by flexible fusion
and fission rates governed by Guanosine Triphosphatases (GTPases) dependent proteins …

Inflammation has been linked to multiple degenerative and acute diseases as well as the
aging process. Moreover, mitochondrial alterations play a central role in these processes …

Obesity is not necessarily a predisposing factor for disease. It is the handling of fat and/or
excessive energy intake that encompasses the linkage of inflammation, oxidation, and …

A number of risk factors for cardiovascular disease including hyperinsulinemia, glucose
intolerance, dyslipidemia, obesity, and elevated blood pressure are collectively known as …