Recent progress and challenges in drug development against COVID-19 coronavirus (SARS-CoV-2)-an update on the status

TM Abd El-Aziz, JD Stockand - Infection, Genetics and evolution, 2020 - Elsevier
Coronaviruses are a large group of viruses known to cause illnesses that vary between the
common cold and more severe diseases to include severe acute respiratory syndrome …

[HTML][HTML] COVID-19 drug discovery using intensive approaches

A Asai, M Konno, M Ozaki, C Otsuka… - International journal of …, 2020 - mdpi.com
Since the infectious disease caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) was reported in China during December 2019, the coronavirus disease 2019 …

Potential antiviral drugs for SARS-Cov-2 treatment: preclinical findings and ongoing clinical research

S Bimonte, A Crispo, A Amore, E Celentano, A Cuomo… - in vivo, 2020 - iv.iiarjournals.org
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), initially termed 2019-new
CoV (2019-nCoV), is a novel coronavirus responsible for the severe respiratory illness …

[HTML][HTML] Current strategies of antiviral drug discovery for COVID-19

M Mei, X Tan - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
SARS-CoV-2 belongs to the family of enveloped, single-strand RNA viruses known as
Betacoronavirus in Coronaviridae, first reported late 2019 in China. It has since been …

[HTML][HTML] A review of SARS-CoV-2 and the ongoing clinical trials

YF Tu, CS Chien, AA Yarmishyn, YY Lin… - International journal of …, 2020 - mdpi.com
The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2) in
Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a …

[HTML][HTML] Drugs for COVID-19: An update

J Ceramella, D Iacopetta, MS Sinicropi, I Andreu… - Molecules, 2022 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the seventh
known human coronavirus, and it was identified in Wuhan, Hubei province, China, in 2020. It …

A review of potential suggested drugs for coronavirus disease (COVID-19) treatment

P Tarighi, S Eftekhari, M Chizari, M Sabernavaei… - European Journal of …, 2021 - Elsevier
The latest pandemic, coronavirus disease-2019 (COVID-19), is associated with high
prevalence and easy transmission, which is expanding globally with no conventional …

[HTML][HTML] SARS-CoV-2: An update on potential antivirals in light of SARS-CoV antiviral drug discoveries

HA Elshabrawy - Vaccines, 2020 - mdpi.com
Coronaviruses (CoVs) are a group of RNA viruses that are associated with different
diseases in animals, birds, and humans. Human CoVs (HCoVs) have long been known to …

Potential therapeutic targets and promising drugs for combating SARS‐CoV‐2

H Zhou, Y Fang, T Xu, WJ Ni, AZ Shen… - British Journal of …, 2020 - Wiley Online Library
As of April 9, 2020, a novel coronavirus (SARS‐CoV‐2) had caused 89,931 deaths and
1,503,900 confirmed cases worldwide, which indicates an increasingly severe and …

[PDF][PDF] Clinical trials for the treatment of Coronavirus disease 2019 (COVID-19): A rapid response to urgent need

T Zhang, Y He, W Xu, A Ma, Y Yang… - Science China. Life …, 2020 - med.uminho.pt
Emerging coronavirus disease 2019, known as COVID-19, is caused by the newly identified
SARS-CoV-2 virus. Since the outbreak of COVID-19 in December 2019 in Wuhan (China) …