Preischemic infusion of alpha-human atrial natriuretic peptide elicits myoprotective effects against ischemia reperfusion in isolated rat hearts

H Okawa, H Horimoto, S Mieno, Y Nomura… - Molecular and cellular …, 2003 - Springer
Carperitide, a synthetic alpha-human atrial natriuretic peptide (ANP) is a newly developed
drug for the treatment of heart failure. However, effects of carperitide on susceptibility to …

α-Human atrial natriuretic peptide, carperitide, reduces infarct size but not arrhythmias after coronary occlusion/reperfusion in dogs

G Takagi, K Kiuchi, T Endo, T Yamamoto… - Journal of …, 2000 - journals.lww.com
Carperitide, a recombinant form of α-hANP, possesses potent diuretic, natriuretic, and
vasodilatory activity, and inhibits the renin-aldosterone system and sympathetic nervous …

Preischemic infusion of alpha-human atrial natriuretic peptide elicits myoprotection through a nitric oxide-dependent mechanism

H Okawa, H Horimoto, S Mieno, Y Nomura… - Journal of …, 2002 - europepmc.org
Objectives Alpha-human atrial natriuretic peptide (alpha-hANP) has been used to treat
patients with heart failure due to its natriuretic and vasodilatory activities. Recent reports …

Atrial natriuretic peptide administered just prior to reperfusion limits infarction in rabbit hearts

XM Yang, S Philipp, JM Downey, MV Cohen - Basic research in cardiology, 2006 - Springer
We investigated whether atrial natriuretic peptide (ANP) given just prior to reperfusion
reduces infarction in rabbit hearts and whether protection is related to activation of protein …

Atrial natriuretic peptide protects against ischemia-reperfusion injury in the isolated rat heart

K Sangawa, K Nakanishi, K Ishino, M Inoue… - The Annals of thoracic …, 2004 - Elsevier
BACKGROUND: Atrial natriuretic peptide (ANP), a stimulator of particulate guanylate
cyclase, has been found to protect against reoxygenation-induced hypercontracture in …

The beneficial effects of atrial natriuretic peptide on arrhythmias and myocardial high-energy phosphates after reperfusion

Y Takata, Y Hirayama, S Kiyomi, T Ogawa… - Cardiovascular …, 1996 - academic.oup.com
Objectives: The aim of this investigation was to test whether the administration of atrial
natriuretic peptide (ANP) has cardioprotective effects against ischaemic and reperfusion …

[PDF][PDF] Experimental study on myocardial protection by adjunct use of carperitide (hANP) in cardiac surgery

S Wakui - Ann Thorac Cardiovasc Surg, 2005 - Citeseer
Background: In recent years, various beneficial roles of human atrial natriuretic peptide
(hANP) have been demonstrated in the internal medicine and surgical fields. However …

Hemodynamic and neurohumoral effects of carperitide (alpha-human atrial natriuretic peptide) in dogs with low-output heart failure

T Hidaka, M Furuya, Y Tani, T Ohno - Nihon yakurigaku zasshi …, 1995 - europepmc.org
We examined the hemodynamic and neurohumoral effects of carperitide in dogs with low-
output heart failure (LHF) produced by volume expansion, ligation of the left anterior …

Haemodynamic effects of atrial natriuretic peptide in rats with heart failure

T Tikkanen, M Svartström-Fraser, I Tikkanen… - European journal of …, 1987 - Elsevier
Plasma atrial natriuretic peptide (ANP), a hormone secreted by the heart, is elevated in
cardiac failure. In the aim to study the role of ANP in cardiac failure, the haemodynamic …

B-type natriuretic peptide limits infarct size in rat isolated hearts via KATP channel opening

SP D'souza, DM Yellon, C Martin… - American Journal …, 2003 - journals.physiology.org
B-type natriuretic peptide (BNP) has been reported to be released from the myocardium
during ischemia. We hypothesized that BNP mediates cardioprotection during ischemia …