TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of prostate cancer cell lines
AI Sagredo, EA Sagredo, V Pola… - Journal of Cellular …, 2019 - Wiley Online Library
Abstract Transient Receptor Potential Melastatin 4 (TRPM4) is a Ca2+‐activated and voltage‐
dependent monovalent cation channel, which depolarizes the plasma cell membrane …
dependent monovalent cation channel, which depolarizes the plasma cell membrane …
[HTML][HTML] Small molecular inhibitors block TRPM4 currents in prostate cancer cells, with limited impact on cancer hallmark functions
A Borgstroem, B Hauert, S Kappel, E Zoni… - Journal of molecular …, 2021 - Elsevier
Transient receptor potential melastatin 4 (TRPM4) is a broadly expressed Ca 2+ activated
monovalent cation channel that contributes to the pathophysiology of several diseases. For …
monovalent cation channel that contributes to the pathophysiology of several diseases. For …
Trpm4 in cancer—a new potential drug target
A Borgström, C Peinelt, P Stokłosa - Biomolecules, 2021 - mdpi.com
Transient receptor potential melastatin 4 (TRPM4) is widely expressed in various organs
and associated with cardiovascular and immune diseases. Lately, the interest in studies on …
and associated with cardiovascular and immune diseases. Lately, the interest in studies on …
TRPM8 puts the chill on prostate cancer
GP Grolez, D Gkika - Pharmaceuticals, 2016 - mdpi.com
Prostate cancer (PCa) is one of the most frequently diagnosed cancers in developed
countries. Several studies suggest that variations in calcium homeostasis are involved in …
countries. Several studies suggest that variations in calcium homeostasis are involved in …
PSA reduces prostate cancer cell motility by stimulating TRPM8 activity and plasma membrane expression
Although the transient receptor potential melastatin 8 (TRPM8) cold receptor is highly
expressed in prostate cancer (PCa) and constitutes a promising diagnostic and prognostic …
expressed in prostate cancer (PCa) and constitutes a promising diagnostic and prognostic …
TRPM8 ion channels as potential cancer biomarker and target in pancreatic cancer
NS Yee - Advances in protein chemistry and structural biology, 2016 - Elsevier
This article provides a review and discussion of the transient receptor potential melastatin-
subfamily member 8 (TRPM8) ion channel as a potential biomarker and target in cancer …
subfamily member 8 (TRPM8) ion channel as a potential biomarker and target in cancer …
Aberrantly over-expressed TRPM8 channels in pancreatic adenocarcinoma: correlation with tumor size/stage and requirement for cancer cells invasion
The transient receptor potential melastatin-subfamily member 8 (TRPM8) channels control
Ca2+ homeostasis. Recent studies indicate that TRPM8 channels are aberrantly expressed …
Ca2+ homeostasis. Recent studies indicate that TRPM8 channels are aberrantly expressed …
Role of TRPM7 in cancer: potential as molecular biomarker and therapeutic target
NS Yee - Pharmaceuticals, 2017 - mdpi.com
The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitously
expressed ion channel with intrinsic kinase activity. Molecular and electrophysiological …
expressed ion channel with intrinsic kinase activity. Molecular and electrophysiological …
Transient receptor potential melastatin‐related 7 channel is overexpressed in human pancreatic ductal adenocarcinomas and regulates human pancreatic cancer cell …
P Rybarczyk, M Gautier, F Hague… - … journal of cancer, 2012 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive forms of cancer
with a tendency to invade surrounding healthy tissues, leading to a largely incurable …
with a tendency to invade surrounding healthy tissues, leading to a largely incurable …
Roles of TRPM8 ion channels in cancer: proliferation, survival, and invasion
NS Yee - Cancers, 2015 - mdpi.com
The goal of this article is to provide a critical review of the transient receptor potential
melastatin-subfamily member 8 (TRPM8) in cancers, with an emphasis on its roles in cellular …
melastatin-subfamily member 8 (TRPM8) in cancers, with an emphasis on its roles in cellular …