Fragile X syndrome is caused by an expansion of the CGG repeat present in the 5'UTR of
the FMR1 gene. A lot has been elucidated about the genetics of the disease, but not much is …

The fragile X syndrome is characterized at the molecular level by expansion and methylation
of a CGG trinucleotide repeat located within the FMR1 locus. The tissues of most full …

Fragile X syndrome results from the massive expansion of a CGG repeat in the 5′
untranslated region of the gene FMR1. Data suggest that the hyperexpansion properties of …

Fragile X syndrome, the most common cause of hereditary mental retardation, results from
amplification of a CGG trinucleotide repeat in the FMR1 gene. The transmission of the CGG …

The fragile X syndrome is the result of amplification of a CGG trinucleotide repeat in the
FMR1 gene and anticipation in this disease is caused by an intergenerational expansion of …

Fragile X syndrome is one of 14 trinucleotide repeat diseases. It arises due to expansion of a
CGG repeat which is present in the 5′-untranslated region of the FMR1 gene, disruption of …

The fragile X syndrome is the most frequent cause of inherited mental retardation. The
molecular mechanism of the disorder is based on the expansion of a CGG repeat in the …

The expansion of CGG repeats in the 5′-untranslated region (5′ UTR) of FMR1 gene is
the molecular basis of fragile X syndrome in most of the patients. The nature of the flanking …

The fragile X syndrome is a common form of familial mental retardation with an estimated
prevalence of 1/4000–1/6000 for males in western countries (1–3). The main clinical …

The fragile X syndrome is associated with an expanding CGG repeat in the 5'untranslated
region of the first exon of the FMR1 gene. Subsequent methylation of the promoter region …